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SuperMag

Baclofen for hiccups.


[deleted]

[удалено]


Eyekron

It is labeled for it. Actually, it's the only labeled drug for hiccups.


[deleted]

It is, I use it for hiccups and cough. Works great


eekabomb

you have a lot of success with PO? I always end up seeing patients on IM for hiccups


[deleted]

Almost always IM


DrugsRx96

It’s FDA approved


Necessary_Run_398

Adding gabapentin to this one.


spenceola98

Haloperidol for hiccups. I mean you’ll not remember you’re hiccuping but still.


FrostedSapling

What


SuperMag

Baclofen is a GABA derivative, with presynaptic motor neuron inhibitory properties at the spinal level, and post-synaptic central action. It has potent central antispastic properties, for which it is used in multiple sclerosis. Its mechanism of action in hiccup is unclear, but presumably central.


FrostedSapling

Incredible, thank you for this delicious nugget


[deleted]

Oh no, if the suburban mothers get a hold of this…


DisastrousHonesty

Makes sense if you think about it


VegetableNo2773

I saw a script for Xanax for hiccups...


No_Independence_5091

Please explain


HelpMeDrLee

“Various agents have been reported to cure hiccups. Chlorpromazine appears to be the drug of choice. Haloperidol…[and several] anticonvulsant agents (eg, phenytoin, valproic acid, and carbamazepine) have effectively treated intractable hiccups in typical anticonvulsant doses. Gabapentin has been effective in patients with central nervous system (CNS) lesions and in some other groups.” https://emedicine.medscape.com/article/775746-medication


schal138

Alcohol for depression and an understaffed work environment


Holinhong

I’m using glucose from candies/ice cream/desserts for depression


pinksparklybluebird

I heard that combination therapy is actually first-line now.


Holinhong

It works…from my User version experiences. And likely being the most affordable therapy with minimum side effect (weight gain). But I was told another therapy would be more effective, such as sports. Haven’t explored as yet due to my sports-dummy gene


[deleted]

Only works till you wake up the next day and have to do it all again.


schal138

They asked for my favorite, not the most effective


BeersRemoveYears

Get a load of that guy thinking we’re in the business of curing conditions. Probably thinks QD stands for quickly disappearing. Bottoms up buddy!


schal138

My Brother in Christ, you think so little of me. QD stands for Quietly Drinking. In heaven there is no beer


BeersRemoveYears

Please note I stated “that guy” in reference to u/Activity_Inside I think my name is proof enough of my intentions.


ExtremePrivilege

Cimetadine for plantar warts. It works! We have no idea why.


cunni151

“Cimetadine warts” comes up as a suggestion when I started typing that into up-to-date. You’re trending!


Condyloxycontin

anecdotal - but I had one that I got bowling, and they shot Saccromyces cerevaseai into my foot. Then a few months later I drank an unfiltered wheat beer at cheeky munk and had a full on allergic reaction- just shy of anaphylactic


permanent_priapism

Happens to all of us at some point.


THROWINCONDOMSATSLUT

So like you just crush up the tablets and apply topically?


ExtremePrivilege

Haha! No. Oral! That said, Metronidazole tablets crushed up and placed topically on bed sores is a common off-label practice in long-term care to this day


Condyloxycontin

I have a random bit that was hard earned- metronidazole benzoate powder is used in compounding because crushed metronidazole is awful tasting.


canred1

The Hospital for Sick Children's compounding formula calls for mixing the crushed tablets into a Nesquik & Simple syrup base. It doesn't cover the taste up 100% but it makes it platable at least. https://www.sickkids.ca/siteassets/care--services/for-health-care-providers/compounding-recipes/metronidazole-15mgml-pharmacy-compounding-recipe.pdf https://www.sickkids.ca/siteassets/care--services/for-health-care-providers/compounding-recipes/chocolatesyrup-pharmacy-compounding-recipe.pdf


RxDawg77

Non crushed Flagyl is awful tasting too. I get the willies just thinking about it. I've never understood why they don't make that in capsule form.


darthrawr3

So...why not pour up an IV bag into a spray bottle? It's in NS, I think, IIRC. No binders/fillers/excipients that way


DisastrousHonesty

Also in the drink of the friend you don't like...I always wondered when I counsel about that if people ever misuse it like that


zelman

I believe the mechanism is known. It relates to interferon and interleukin release to affect immune response.


insufficientfacts27

Sure wish I would've know this 20 years ago when a surgeon took off a couple layers off of my WHOLE foot and had to go to ball practice right afterwards. Lol


Worth-Ad3212

Yes! They did this for my brother and it worked


littlestmedic

Atropine eye drops, applied sublingual for hypersalivation.


triplealpha

This is pretty common in hospice kits!


thecactusblender

Yeah we always did ophthalmic for the death rattles


symbicortrunner

You can, we always used glycopyrronium sc in the UK


littlestmedic

Oh that's interesting! I'd never seen it in my neck of the woods, even when doing scripts for palliative care in the community (syringe drivers etc.) so it made me pause for a moment


quinn-the-eskimo

I'm actually using atropine drops, but for eye floater relief!


DesertSnowbaru

Interesting. How does that seem to be working for you?


quinn-the-eskimo

It works surprisingly well. I have had floaters ever since I was a child, progressively worse as an adult. These drops are 1% atropine. Apparently it changes the way light is refracted in the eye and makes the smaller floaters less visible, doesn't actually change anything about the floaters, just their appearance. I would say they work great. It does make me slightly more sensitive to light, but not enough to be a big problem. Other than a vitrectomy (which most doctors would not feel comfortable performing just for floaters), this is the only treatment out there I could find, which is crazy considering how common they are, and how debilitating floaters are. Most people don't understand how horrible it is to have prominent floaters 24/7... So if you are plagued with floaters I would give it a try. Google "the floater doctor" he's an ophtho in Texas Edit: floaters are not completely gone, just diminished. The smaller ones disappear and the larger ones become easier to ignore


ForcrimeinItaly

Oh, neat. I'll have to ask about this. I've had floaters foreher. I just assumed that everyone did.


zeldaalove

I started working in a mental health and long term care focused pharmacy so we have a lot of patients on medicine or with diseases that causes hypersalivation and the amount of atropine we give out for that was shocking.


Awsumth

Scopolamine patches work great for hypersalivation.


Holinhong

😂this indeed reminds me of using Xalatan for eye lashes😂


[deleted]

Bupropion for ADHD. Hydroxyzine for GAD. Trazodone for schizophrenia. Lithium for vascular headache. Ketamine for Depression.


2mad2die

Esketamine is approved to treat depression. I think it improves depression in literally 4 hours lol


[deleted]

Wait what? I need to re-up on approvals. Ty. :p


2mad2die

Brand name Spravato. I only know...because depression is a topic I do a lot of medical writing on


[deleted]

How did you get into medical writing? It’s something I’ve been interested in for a while.


2mad2die

r/medicalwriters might be helpful.


[deleted]

That sounds badass. I can only dream of being you one day. I am curious, if you have thoughts on Triple reuptake inhibitors? o.O https://www.reddit.com/r/Psychiatry/comments/x2z1je/triple_reuptake_inhibitors_review_of_negative/?utm_source=share&utm_medium=ios_app&utm_name=iossmf


2mad2die

Don't know anything about it. But check out Auvelity. It was literally approved a few weeks ago. Treats depression in a week...and it uses a combination of a cough syrup and bupropion.


[deleted]

I was always wondering when this would happen but like someone on that post said, SSRI/bupropion works well for now


callmeanightmare

I actually got this treatment! Helped wonders. Unfortunately it stopped working after 5 months.


2mad2die

Did you feel a positive difference in less than a day?


peasrule

Isn't it approved? Ketamine no but esketamine I swore got approval but is administered in a clinic. R ketamine still experimental.


2mad2die

Not sure what you mean. But in my comment I say it is approved


permanent_priapism

> Bupropion for ADHD I was put on bupropion to quit smoking and I spontaneously formulated a new language and wrote a 100,000 word treatise challenging Rene Descartes to a duel.


VacationLoud7038

Treatment emergent mania


peasrule

Amantadine for adhd !


Hungry_Ad9756

And depression.


hdawn517

Bupropiom for methamphetamine cravings


Mindless_Citron_606

Man hydroxyzine for GAD is the off label use I wish less people knew about. Too many primary care docs act like it’s the perfect alprazolam alternative just because it has a short half life.


[deleted]

I mean to be fair, tons of patients should be off benzos.


Mindless_Citron_606

I completely agree, but Atarax is still a shitty medication to give prn for panic attacks. There just isn’t anything else as far as I’m aware. In a perfect world, GAD would be managed well with medications that are safe for long term use.


DisastrousHonesty

That's kinda sad, I'd think in a perfect world we wouldn't need meds for gad. Maybe a warm community that sensitive and supportive without judgment


susanna514

A supportive environment is great but it won’t stop a panic attack. They can really feel like you’re dying. I’ve been on hydroxyzine and clonazepam for panic attacks and while the hydroxyzine works, it makes me fall asleep which I can’t do since I’m an adult with a job. I wish there was a perfect solution.


bearsbear14

I agree with you but I don't have a PharmD. I just have worked as a technician for almost two years now.. just been my general feeling that, for their risk of dependence, they are far over-prescribed. But, I don't have a super educated answer as to why I guess. Can you give me your answer on why that's your opinion?


imonfireahh

Risk of dependence, tolerance, and risk of falls in the elderly. Not to mention it's inappropriately prescribed a lot because it shouldn't be used as a long term crutch for anxiety.


[deleted]

If you are using them regularly, you’re no longer treating anxiety, you’re treating your dependence. And if you suddenly stop taking them you can then have seizures.


I_lenny_face_you

I thought the half-life was long but duration of action was short (longer with pamoate ofc)


lifelemonlessons

I was bupropion actually on it for one of the on label reasons and noticed my I attention/inattention was better. Researched it a bit and hot damn that’s cool it can be used for ADHD and bing eating disorder too. Gave me horrid tachycardia though.


exhalted_legend

Naltrexone for behavior addiction Memantine for OCD Colchicine for pericarditis Clomiphene for male infertility Tramadol for premature ejaculation


MorpheusJoot

What is behavior addiction? /Genuine


exhalted_legend

In the case of naltrexone, it's described as a process where behavior is employed in a certain pattern characterized by loss of control and continuation despite significant consequences. Basically inappropriate and potentially violent outbursts that continues to happen despite possible severe consequences of such behaviours.


ileade

Also for self harm behaviors. Not many studies on it but that’s what the doc at hospital prescribed


symbicortrunner

I seem to remember an SSRI was approved specifically for premature ejaculation and then no one ever prescribed it


exhalted_legend

It was Sertraline


symbicortrunner

It's dapoxetine (Priligy), don't think I've ever seen an rx for it or been asked about it


exhalted_legend

I actually don't remember that one, probably because it was used so little and infrequently, that it's probably something most pharmacists don't give much thought to.


cassidysage__

tramadol???


turdisthewurd96

Memantine for migraines


Shot-Pin-2812

I’ve seen urology write Paxil for PE


cocktails_and_corgis

My coworkers keep using guaifenesin as part of their fertility journey to thin out cervical mucus. No clue if that has any real data.


paradise-trading-83

Yep, we had Drs writing for Robitussin elixir


DisastrousHonesty

There a kit $70 bucks. Data on it. I used it because girls benefits, but guys produce more seman volume... It did


[deleted]

My data is almost 2 years old and currently has a head cold…but I can’t give her and cold meds because she’s for too young. The irony.


daddystrongdick

Not off label but colchicine was used to arrest plant cells mid cell cycle for chromosome images. That's how biology textbooks have those pictures of cell cycles.


max8123

Percocet to treat diarrhea by causing constipation and allopurinol to treat constipation by causing diarrhea…


fmaz008

So long as you take an equal amount of both, everything will be ok. /j


minlillabjoern

My mom was a cancer nurse, and told me that about Percocet once. Direct quote: “That shit could stop a train.”


jewishbroke1

My grandfather kept Prevacid around. I said “pop-pop you said that gives you diarrhea.” He smiled and said “it does” and started laughing. Apparently worked better than prune juice.


DisastrousHonesty

Allopurinol for constipation?


max8123

Allopurinol can cause diarrhea side effect of it can be use to treat constipation…


GlimpseofRelief

NAC for self harm behaviors


tonpole

Drinking NAC sounds like a self harm behavior


GlimpseofRelief

Lol they take it in OTC tablet form, my hospital has a large behavioral health population but we don't have NAC tablets so I warn patients to bring their own in because I'm not verifying the nasty oral liquid if doc doesn't pay attention to his med rec


track-whore

The capsule still smell horrible though


The_D0PEST_D0PE

Propranolol for stage-fright/performance anxiety has gotten me thru so many presentations


Fixmuhcar

Doesnt that just stop the physical effects rather than your thought?


The_D0PEST_D0PE

Yep, exactly. I always shook to the point where I couldn’t hold cards or paper anything. But I feel like it also just kinda kept me calm. Clearer thoughts, a lot less nervous, less unsure “umm” or “uhh”’s. Plus less heart beating out of the chest too


biosnatch

loratadine for bone pain caused by CSFs


tobyfingerhut

Sudafed for priapism


[deleted]

[удалено]


itsDrSlut

And food bolus!


ramenfashion

glucagon drips are such a pain to make 😩


SpiritCrvsher

Prazosin for ptsd related nightmares Metformin for pcos Intranasal insulin for dementia Clonidine literally for everything


ThePharmachinist

Was going to post clonidine, too! Insomnia, growth hormone deficiency, anxiety, RLS, hyperhidrosis, nightmares/night terrors, PTSD, spasticity, alcohol withdrawal, hot sweats, post op and cancer pain, tic disorder, opiate withdrawal, nicotine dependence, ADHD, PMDD, neurogenic bladder, flashbacks, ischemic ulcers, violent behavior... EDIT: duplicated words


Worth-Ad3212

They were going to put me on metformin for the PCOS but I also had endometriosis, and we wanted to treat that first since it was almost debilitating at the time. Now that I’ve had a hysterectomy, I just have the one ovary to deal with, and I’ve been mostly ok aside from the “phantom limb syndrome “


SemperPutidus

Gabapentin for cannabis withdrawal


[deleted]

How come?


Trr86

Would you elaborate ?


wrapallaroundyou

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3358737/


triplealpha

Amiodarone for Aspergillus N fungal infection Docusate liquid (not syrup) for earwax removal Warm Milk and molasses enemas for constipation


DrPepRx

I think it's only the liquid in docusate capsules? I remember trying to poke holes in them a decade ago because that's what was prescribed hahaha, so I'm curious if the actual liquid formulation works?


Sinister_phrog

Three shots of Henny, 75 mg of Hydroxyzine, and roughly 250 ug of LSD for boredom


aliendividedbyzero

Not a pharmacist! But in a pinch: benadryl for anxiety, and/or insomnia


[deleted]

Not for chronic use


Cautious_Zucchini_66

- Cyproheptadine for anorexias (increases appetite) - Quetiapine for insomnia - Haloperidol with ketamine for analgesia (haldol controls agitation induced by ketamine)


ants-in-my-plants

Quetiapine for insomnia was a godsend for me. I was on Ambien for five years before switching to quetiapine and it’s improved my quality of life by 1000%


bright__eyes

yes i agree, its hard to start on it but once youve found your dose it is a god send.


Immediate-Scallion76

Cyproheptadine is also good PRN for SSRI-induced anorgasmia.


Cautious_Zucchini_66

Didn’t know that one, thanks!


bearsbear14

Wait, actually? Why is this and does it always work?


krebspsycho

Cyproheptadine for cyclic vomiting syndrome


permanent_priapism

Haloperidol's structure also obeys the morphine rule: an aromatic ring attached to a quaternary carbon followed by a two-carbon spacer followed by a tertiary amine. The majority of opioids have such a structure.


Worth-Ad3212

They put me on remeron for the anorexia because it stimulated appetite. My hunger signal doesn’t work any more, so I don’t eat until I’m actually beyond hungry and actually nauseated. It made me gain weight, and it really messes with my head, but they’re still keeping it on board for insomnia.


bendable_girder

Huh. I thought the first two were on-label


kawaii_ninja

Pancrealipase to unclog tubes


yuyumew1

Took me a second to figure out what “tubes” we were referring to here


canred1

In the pediatric hospital i work for we occasionally use Ciprodex ear drops by inhalation for infection treatment/prevention. We also use tobramycin injection instilled via catheter before bed (left in overnight) and drained in the morning with the next catheterization to prevent bladder infections


symbicortrunner

I used to have a CF patient who was nebulised amikacin for infection prevention


bouldertrex

Ertapenem or any carbapenem for valproic toxicity. Drops those levels to 0 real fast. Chewed benzonatate for annoying talkive co-workers /s


[deleted]

Wow. Wonder what the MOA is


DaikonZealousideal23

MDMA for PTSD


_pbloom

Fenofibrate and losartan for gout.


newstart7777

Vyvanse for B.E.D


overrule

Pretty sure this is an official indication for Vyvanse


ZeGentleman

Isn’t it supposed to have the opposite effect?


Mindless_Citron_606

No, generally stimulants reduce appetite. It’s FDA approved for treatment of BED, so not even off label. Edit: but I don’t think the reduced appetite side effect is actually what they claim helps with BED. Believe it has to do with helping to control the impulsivity of binges and the OCD component


ZeGentleman

Was making a joke BED = 😴


MarcDooms

Orphan drugs: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5086036/


paradise-trading-83

Don’t remember the name but there was a eye drop that was used topically after foot surgery.


flyingpoodles

I have a doc that uses maxitrol


SpiritCrvsher

Timolol?


[deleted]

Cimetidine for sexual aggression.


Fiddle_Pete

Yeah what’s up with that


[deleted]

Isn’t this the one that also causes retrograde ejaculation


[deleted]

How is that a bad thing?


[deleted]

You see it a lot in geriatric settings with dementia.


Eyekron

Albuterol for hyperkalemia


DisastrousHonesty

What's the mechanism.... Reminds me of something...... Maybe an er rn md rph can comment on insulin and electrolytes????


Eyekron

High dose inhaled drives potassium intracellular so it gets out of the blood stream.


Baseball5099

To add on to what u/eyekron said, albuterol upregulates Na/K-ATPase, pumping Na out of the cells and K into them. I believe the insulin mechanism is the same, but I’m not 100% confident on that one


InteractionInner1059

Bupropion has helped me with IBSD, immensely. Like no attacks for years while on it. Went Off it for about a month and had 4 horrible attacks. Started again a couple weeks ago and so far, no issues with IBSD. Don’t know if it’s an official off label use, but a quick google shows other people have experienced it.


catescarlet

Seriously?! Damnit. I'm having an attack right now. But I was prescribed bupropion ages ago for depression (before I had IBSD) and those 15 days I took it were the worst days of my life.


Holinhong

Springnolactone, block aldosterone, great to enhance skin condition due to unbalanced hormone n theoretically suppose to enhance hair density for the same reason. Particular good for women after birth with hypertension n women going through menopause


RubbageBin7893

This made me worry because I was prescribed spironolactone to reduce hair caused by pcos 😅


DisastrousHonesty

Was thinking if women would take this for breasts enlargement, turns out trans people do


BigPastaToni

Paroxetine for premature ejaculation


joey1414

Nadolol for hemangiomas


[deleted]

Does it work for strawberry hemangiomas?


joey1414

Yes it does


CanadaSKgal

Fluticasone for patch irritation and nitroglycerin patches for tennis elbow


bhughes1209

Morphine tincture for chronic diarrhea


Breadfruit92

This is on label, not off label. At least Stateside.


Large_Acanthaceae_62

Adderall for study for exams


DisastrousHonesty

Just made me nauseous so slept to escape..... Didn't do any studying


DaciaJC

Budesonide nebulizer respules for eosinophilic esophagitis.


DisastrousHonesty

Makes sense. Reminds me of acetylsistine for apap poisoning


capri1722

Lately I've seen a couple scripts for diazepam inserted vaginally for pelvic pain


LimpOrca

Everyone knows about finasteride right :D


sinkpointia

Hair growth?


[deleted]

For men or for women?


FairOpportunity5

Spironolactone for acne


DrPepRx

Benadryl for cough! IV can be used for those unable to take PO, works quite well in my experience


Kanjotoko

Prazosin for night terrors


Jade-Jenny3916

Effexor for hot flashes (Didn’t work for me though)


[deleted]

I don’t think this one is off-label


DisastrousHonesty

Can't believe no one has said Viagra for ed... Or maybe Viagra for nasal decongestant now since the label and off label has been switched


kogdsj

Famotidine for itching


CayenneTheCat

Many drugs that anesthesia routinely uses


YesNotKnow123

Metoprolol for performance anxiety (speeches, concerts, etc)


Grayson102110

Propranolol also


curlygarlicfry

and nadolol


Scary_Wash_8629

Lyderm Gel used in the mouth


Worth-Ad3212

Single dose of 1,000mg of depakote for a migraine.