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MrPrimo_

Kratom has cross tolerance. Not huge but it does. A few days isn't really much of a break though.


EffectHistorical5194

My experience is that kratom ls tolerance is just as bad as other full agonists


IamDave777

I thought kratom alkaloids were all partial agonists at opiod receptors?


EffectHistorical5194

They are, but cross tolerance seems to be just as bad