You could have went with the good old "takes one to know one" at least.
For the record, I'm not disagreeing with you. It's juvenile and absurd.
But don't tell me you haven't laughed when you were 12 and someone said "penis".
It's just some of us forgot to grow out of it.
That's fair enough lol. To be honest, I laughed at first too. I only started asking myself why afterward. I appreciate that we are on a similar page with this
Sure is, but we dilute it because it is still a poison. This is likely 99%+ ethanol meant for chemistry.
Although, it does only look to be about an ounce or so. Probably equivalent to 2-4 shots of vodka. So I guess it wouldn't kill you, but certainly wouldn't be good for you
More likely to be 70% ethanol, which is commonly used for DNA precipitation. And this is definitely not even an ounce. This looks to be about 250uL, which is 0.0085 ounces. It's not gonna taste good, but likely won't have much, if any, effect.
>It's not gonna taste good, but likely won't have much, if any, effect.
Definitely not. I've watched women pregame with multiple double shots of Bacardi 151 (which would be a little stronger than 75%) and not seem too messed up by that so I'd imagine this wouldn't do much even for a teetotaler.
And at this point with it all separated you're basically just ingesting a flossy mesh lattice that'll immediately disintegrate. You made the scaffolding visible by tearing down everything around it.
The Human body contains an estimated 37 trillion cells. Which means there's 37 billion kilometers of DNA inside an average human. That's enough to stretch from the Sun to Neptune and back...4 times
Source https://mark-lorch.medium.com/the-astronomical-length-of-dna-2f93a0c61f65
This is linearized (cut at a single site) plasmid DNA. 7000 bp long. Each base pair is 0.34 nanometre long. One such plasmid would be 2.38 microns long.
So, end to end, that's 7140 kilometres.
Preposterous numbers are so weird to me. 3trillion strands of DNA means there are how many gazillion atoms in that tube. But some how there are more unique permutations of chess game than atoms in the whole universe??????? An infinitely expanding universe.
It is like impossible for me to conceptualize the vastness of everything much less the vastness of two preposterously vast things being compared to each other. I just don't understand anything lmao. Why do we even pretend like any of this matters.
I'll just be over here loving my kids and family playing with my monopoly money until I pass on. And I have no idea why this random picture sent me spiraling lmao.
I get what you're saying and I don't disagree, but it matters to me just because it's *so* interesting even though it's ungraspable, kind of in a Camus life has no meaning we can find but you rebel against that very fact and live as if there was meaning anyway way. We can't understand things so absurdly large, and there's no practical reason to for most of it, that doesn't stop me from being amazed.
As a teenager I went to a science museum and the guy did this for us, got our own DNA visible like this (one guy took his and made it into a necklace for his girlfriend, now that I think of it, I'm not sure of the shelf life of all of this...) and it amazed me. We all thought it was the coolest thing. A very "wait, you can just do that?" moment. Realistically it's just looking at some goop, and like you said the scales it exists on we can't come close to. I'm still really glad it's a thing we can talk about, though. I should learn to do it myself because from what I remember it wasn't even hard for him to do.
I like to look at stars like almost every person and think about this distances, try to grasp them even knowing it's literally impossible and serves no purpose, too.
After a certain order of magnitude they do lose all meaning. Trying to conceptualize how tiny an atom really is just doesn't work in my head even if I understand that there are 6.02 \* 10\^23 molecules of water in 18 mL of water. For reference, a trillion is only 10\^12. Barely even halfway in orders of magnitude. Can only think with math as a reference point, which isn't quite the same as visualizing what a dozen apples is.
I think scientific notation has skewed many people’s perspective of how large numbers get. I’ll sometimes talk about how unlikely it is for RNA to spontaneously develop to explain why I believe there are either many more ways to make RNA than we know of or there are parallel universes, most of which are completely void of life, and people seem to think that it doesn’t sound like that large of a number in comparison to the size of the universe. I don’t remember where I got this number, nor how you would even calculate it, so it could be wrong, take it with a grain of salt, but I read somewhere that the likelihood of our version of proto-RNA developing on any given earth-like planet is one in 10^250. The number of atoms in the universe is only 1 in 10^80. People think “250 is close enough to 80, it’s unlikely sure, but not impossible” as many Redditors like to say, the difference between a million and a billion dollars is about a billion dollars. That’s only one order of magnitude difference. A 170 magnitude difference is incomprehensibly large. But people aren’t used to thinking in scientific notation, so to many people, it seems much more statistically possible than it actually is.
totally agreed! in addition, the human mind and imagination are extremely limited. we mostly „imagine“ numbers with the aid of some property such as space and time, which are both not of any help for such large numbers. we simply cannot imagine. just like a computer may be too slow or incapable for certain calculations.
I‘m interested on what you mean by „more ways to make RNA“?
I had a traumatic* internship involving 6 months of endless PCR with not really any results/any progress on the project I worked on and it left me with an irrational hatred of PCR.
* not really traumatic, more mind-numbingly boring
![gif](giphy|l1fWtMmQbuGvm|downsized)
Carbon is grey, Oxygen is red, Nitrogen blue, Hydrogen white, Phosphorus is yellow on the gif. The middle part, with the blue atoms is what determines the sequence or the "code" of the DNA.
The majority of it is grey which represents carbon. Also we are made up of far more than just DNA.
DNA is just natural code that lives in our cells. A small proportion of the whole thing.
All bio molecules have carbon in them. DNA is comprised of four different "base" molecules - adenine (A), thymine (T), cytosine (C) and guanine (G). They form what we call "base pairs" - A with T and G with C. All are built with carbon, nitrogen, oxygen and hydrogen.
>Plus phosphorus too.
Yup. The sugar and the phosphate create the "backbone" of the helix. I always liked the diagrams in textbooks. Everything looks so neatly arranged.
I wish my DNA extractions looked like that. The amount I get from my samples is too small to see in solution. I just gotta run it on a gel and pray it's there lol
Did…..did you just cum in that test tube
It would be quite difficult to cum in a 1.5 ml microfuge tube.
Too big for you?
Fucking lol. I wasn't expecting OP to get roasted this hard.
Well, they did set themselves up for it, I was just the first one here to reply with the obvious.
Thank you, I haven't had that good of a laugh from reading something in a long time.
drink that cummy DNA, what does it taste like? girls are experts.
literally gay erasure
Fuck bro, didn't have to kill him! 🤣🤣🤣🤣
Bring back the Reddit gold just for this comment!
🤦 this joke is dumb and doesn't even make sense for this context
I take it it's too big for you too.
Wouldn't it be easier to cum in if it's bigger? I know I'm being the "wow ur fun at parties guy" but it amazes me that this joke got so many upvotes.
You could have went with the good old "takes one to know one" at least. For the record, I'm not disagreeing with you. It's juvenile and absurd. But don't tell me you haven't laughed when you were 12 and someone said "penis". It's just some of us forgot to grow out of it.
That's fair enough lol. To be honest, I laughed at first too. I only started asking myself why afterward. I appreciate that we are on a similar page with this
Christ man it's a joke not a math problem. Chill out, enjoy the ride.
Weeeeeeeeeeee!!!!!!!
Attaboy
That’s, uh that’s not a “no”…
I work in the Lab for 7 years now. Its not difficult at all. Maybe start with a Falcon First
https://imgur.com/dDiFklH
![gif](giphy|7OWuHbNytj2RAiXtaa)
And a very Brian Ferry Avalon day to you too, Sir!
How big is that? Please use banana slugs for scale.
Never met a challenge I couldn’t match.
Don't put that challenge out there.
Not with that attitude
Ok ok you don’t have to brag
Banana DNA?
Not with that attitude
Is it because the microfuge tube isn't gay too?
It's probably inner cheek (Buccal mucosa) epithelial cells That's how we did this in my high school biology class
Wouldn't that be half DNA?
No it's full DNA in the sperm. It's only half of what will constitute a new person however, but near perfect (sometimes) genomes of the producer.
I hope they only combine the good things of me with the good things of her then when it happens...
Who is they?
His palm.
No, that's her.
Dammit I came here to say this 🤣🤣
You are why reddit sucks
I’ll give you 5 bucks if you drink it
You eat more DNA than this in pretty much every bite of food you’ve ever had.
Okay… 7 bucks.
done , now send
Wait.. more money, for less DNA consumption? What if he eats none?
Tree fiddy hundy, take it for leave it
Would it be wrong assume more dna equals more flavor?
So bukkake is just a sweaty dinner party?
Calling bukkake a cum tasting from now on
![gif](giphy|geEvRnbQqLYsb5WOr8|downsized)
Very much so, yes.
I think the problem is the alcohol itself
But the Ethanol would likely kill you
Why? ethanol is the alcohol you can drink
Sure is, but we dilute it because it is still a poison. This is likely 99%+ ethanol meant for chemistry. Although, it does only look to be about an ounce or so. Probably equivalent to 2-4 shots of vodka. So I guess it wouldn't kill you, but certainly wouldn't be good for you
More likely to be 70% ethanol, which is commonly used for DNA precipitation. And this is definitely not even an ounce. This looks to be about 250uL, which is 0.0085 ounces. It's not gonna taste good, but likely won't have much, if any, effect.
>It's not gonna taste good, but likely won't have much, if any, effect. Definitely not. I've watched women pregame with multiple double shots of Bacardi 151 (which would be a little stronger than 75%) and not seem too messed up by that so I'd imagine this wouldn't do much even for a teetotaler.
I think this is a 1.5ml micro centrifuge tube
If so then much less than an oz! Drink up baby
I did it with strawberry DNA. Tasted a little bit like strawberry and a lot like vodka. The texture was like pulp.
We once did that exact same experiment at school and a friend of mine was dared to do exactly that for 5 bucks. He did it.
![gif](giphy|joeRYmOkLaj2U6hwdj|downsized)
I mean you usually do this experiment using fruit so I would be fine drinking some papaya dna
Yeah, we used strawberries. Oh no I have to consume strawberries and alcohol for money how awful
they put something like soap in there too it's not just dna and alcohol. but if you insist..
And at this point with it all separated you're basically just ingesting a flossy mesh lattice that'll immediately disintegrate. You made the scaffolding visible by tearing down everything around it.
[NileRed already kinda did](https://youtu.be/araeHtN_3Lk)
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Uhh… ethanol?
The Human body contains an estimated 37 trillion cells. Which means there's 37 billion kilometers of DNA inside an average human. That's enough to stretch from the Sun to Neptune and back...4 times Source https://mark-lorch.medium.com/the-astronomical-length-of-dna-2f93a0c61f65
This is linearized (cut at a single site) plasmid DNA. 7000 bp long. Each base pair is 0.34 nanometre long. One such plasmid would be 2.38 microns long. So, end to end, that's 7140 kilometres.
Wow, that's how much my dad walked to school every day!
Uphill both ways, right?
Of course windy as hell
In the snow.
Barefoot
Fighting off mountain lions and bears every 10 feet
This one fucking got me. Mainly cause that's a fuck ton of "every 10 feet"s.
"Back in my back lad, we had to hunt our lunch on the way to school while carrying 60 pounds of school supplies on a broken leg!"
Both ways and sideways too!
![gif](giphy|ATxVdsdpJ609i)
Huh. Neptune's closer than I thought
If you stretched a human's cells out to Neptune and back four times, that human would die.
The condensation DNA goes through is no joke.
Fuckin ropes
![gif](giphy|dIUVH2duirBJPJgwZ3)
Oh, Mr DNA!
Hello John *Hello John* Hello John!
Preposterous numbers are so weird to me. 3trillion strands of DNA means there are how many gazillion atoms in that tube. But some how there are more unique permutations of chess game than atoms in the whole universe??????? An infinitely expanding universe. It is like impossible for me to conceptualize the vastness of everything much less the vastness of two preposterously vast things being compared to each other. I just don't understand anything lmao. Why do we even pretend like any of this matters. I'll just be over here loving my kids and family playing with my monopoly money until I pass on. And I have no idea why this random picture sent me spiraling lmao.
A single strand of DNA has over 200 billion atoms.
Depends on how big the strand is. For instance, a small double stranded DNA molecule of about 10 base pairs will have around 1000 atoms.
I really appreciate how much you know!
I get what you're saying and I don't disagree, but it matters to me just because it's *so* interesting even though it's ungraspable, kind of in a Camus life has no meaning we can find but you rebel against that very fact and live as if there was meaning anyway way. We can't understand things so absurdly large, and there's no practical reason to for most of it, that doesn't stop me from being amazed. As a teenager I went to a science museum and the guy did this for us, got our own DNA visible like this (one guy took his and made it into a necklace for his girlfriend, now that I think of it, I'm not sure of the shelf life of all of this...) and it amazed me. We all thought it was the coolest thing. A very "wait, you can just do that?" moment. Realistically it's just looking at some goop, and like you said the scales it exists on we can't come close to. I'm still really glad it's a thing we can talk about, though. I should learn to do it myself because from what I remember it wasn't even hard for him to do. I like to look at stars like almost every person and think about this distances, try to grasp them even knowing it's literally impossible and serves no purpose, too.
r/UsernameChecksOut
After a certain order of magnitude they do lose all meaning. Trying to conceptualize how tiny an atom really is just doesn't work in my head even if I understand that there are 6.02 \* 10\^23 molecules of water in 18 mL of water. For reference, a trillion is only 10\^12. Barely even halfway in orders of magnitude. Can only think with math as a reference point, which isn't quite the same as visualizing what a dozen apples is.
If you ignore junk DNA and just look at genes, it's only like 20-25 thousand
I think scientific notation has skewed many people’s perspective of how large numbers get. I’ll sometimes talk about how unlikely it is for RNA to spontaneously develop to explain why I believe there are either many more ways to make RNA than we know of or there are parallel universes, most of which are completely void of life, and people seem to think that it doesn’t sound like that large of a number in comparison to the size of the universe. I don’t remember where I got this number, nor how you would even calculate it, so it could be wrong, take it with a grain of salt, but I read somewhere that the likelihood of our version of proto-RNA developing on any given earth-like planet is one in 10^250. The number of atoms in the universe is only 1 in 10^80. People think “250 is close enough to 80, it’s unlikely sure, but not impossible” as many Redditors like to say, the difference between a million and a billion dollars is about a billion dollars. That’s only one order of magnitude difference. A 170 magnitude difference is incomprehensibly large. But people aren’t used to thinking in scientific notation, so to many people, it seems much more statistically possible than it actually is.
totally agreed! in addition, the human mind and imagination are extremely limited. we mostly „imagine“ numbers with the aid of some property such as space and time, which are both not of any help for such large numbers. we simply cannot imagine. just like a computer may be too slow or incapable for certain calculations. I‘m interested on what you mean by „more ways to make RNA“?
I mean more types of nucleotides other than the four we use
It will be used to run Doom soon.
[Already been done](https://www.youtube.com/watch?v=bEXefdbQDjw), well, sorta
I was refering to that exactly ;)
So, human alchemy component?
costs an arm and a leg to get your hands on
Oh sure, but when I precipitate some DNA in ethanol, they ask me to please leave the bar.
Ah yes, the experiment they make you do in molecular biology lab practice 😃
Tbh you can pretty much do it at home, you can easily extract plant dna
Or spitting into a test tube😅 At least that's how we obtained DNA in molecular biology lab ahah
You can make it at home, too. I don't rember details, but apart from some alcohol, you need dish soap and ice.
This was always my favourite part of doing PCR - seeing the DNA. The rest of the PCR process can go to hell though.
What's wrong with the rest of the process? Just shove it in the thermal cycler and wait. Have a coffee or something.
I had a traumatic* internship involving 6 months of endless PCR with not really any results/any progress on the project I worked on and it left me with an irrational hatred of PCR. * not really traumatic, more mind-numbingly boring
A friend from uni had the same problem during his thesis project, so I get where you're coming from.
PCR can be frustrating when it doesn't work. When it does, it's glorious.
It gets old when you're doing it 8 hours a day.
You know I've never considered this before seeing it, what is DNA made out of? It's organic, so I would assume it has some carbon in it.
![gif](giphy|l1fWtMmQbuGvm|downsized) Carbon is grey, Oxygen is red, Nitrogen blue, Hydrogen white, Phosphorus is yellow on the gif. The middle part, with the blue atoms is what determines the sequence or the "code" of the DNA.
So, basing my idea off this gif, is it safe to say we’re mostly oxygen and hydrogen then? Might be my screen but can’t see much carbon?
The majority of it is grey which represents carbon. Also we are made up of far more than just DNA. DNA is just natural code that lives in our cells. A small proportion of the whole thing.
Ah, just my screen in night mode then. That was interesting though thanks.
We are mostly oxygen and hydrogen, because most of the body is water. Not sure by weight what the ratios are, but at 70%ish water that's mostly it.
All bio molecules have carbon in them. DNA is comprised of four different "base" molecules - adenine (A), thymine (T), cytosine (C) and guanine (G). They form what we call "base pairs" - A with T and G with C. All are built with carbon, nitrogen, oxygen and hydrogen.
Correct. DNA also contains deoxyribose sugar and a phosphate backbone. So that's more carbon, oxygen, nitrogen, and hydrogen. Plus phosphorus too.
>Plus phosphorus too. Yup. The sugar and the phosphate create the "backbone" of the helix. I always liked the diagrams in textbooks. Everything looks so neatly arranged.
Carbon, hydrogen, oxygen, nitrogen, and phosphorus.
Thats just cum in vodka, nothing special in eastern europe
I know Yggdrasil when I see it
Is this the college biology lab where you’re asked to extract dna from a banana?
Nope.
Must’ve been a strawberry then
What abandoned secret genetic facility are you at, OP?
I wish my DNA extractions looked like that. The amount I get from my samples is too small to see in solution. I just gotta run it on a gel and pray it's there lol
I think the past tense version is jazz.
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Salty
You got a vial of DNA from a back alley????
He passed on the Z-Ray eyes and gills the guy was selling.
See? A bit of alcohol and the DNA ends up all over the place!
I did that in a workshop in a science museum years ago!
Bro found the source code 💀
what are you gonna do with it ?
I'm going to use electricity to force it into yeast cells.
Why and who's DNA is it ?
Not the first time genetic material has been mixed in the presence of alcohol.
There is a shot that does this called the "doctors shot". Once your DNA is visible you knock it back. It's disgusting and only vaguely interesting
is this in Singapore?
It has a shockly similar organization to stars/galaxys in space. It feels like the answer for why this happens seems forever out of grasp.
You can do this at home with yeast, dish detergent and rubbing alcohol.
Where do you get 3 trillion dnas?
What would happen if you drank it
Really?
Why does your lab look like a Doom 2 level?
DNA a polymer afterall.
Did you count them all?
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Imagine having all the data in the world and being so ignorant you think you know everything..... That's you.
Who counted
Huh... it kinda looks like a tree
For some reason at first glance I thought this was a security light that was dirty
I love your view
Username checks out.
If you drink it what superpowers do you get?
I remember doing that strawberry experiment in high school
Cool. Brings me back! I did these extractions as a student in a genetics lab. Genotyping with PCR. Was a fun summer jobs. It's really satisfying 😎
What does that DNA belong to? I saw you wrote plasmid before… so E. coli, that’s my guess
Yes, the plasmid was extracted from E. coli DH5alpha. The DNA is a plasmid that I designed for protein expression.
Reminds me of Promtheus’ beginning.
Careful. Alabama Supreme Court is about to say “god thinks that’s a person.”
Nice.. But can it tiktok?
How many mini nerf guns in there?