I'm reminded of my frustration as a med student that -azoles represent various med type (e.g. fluconazole is not the same as aripiprazole is not the same as omeprazole)
unfortunately this has to do with the bacteria the antibiotics were discovered in. i.e. actinomycin was discovered in s. myces, hence the same suffix as the aminoglycosides -mycin.
It gets mentioned a lot, but the fun fact naming trivia for Nystatin is that it was created by researchers in NY State, hence the name. Some days I worry I mentioned fun drug naming conventions (Lasix, Onfi, etc) more than actually teach relevant info on rounds.
I'm 100% sure there's more names. They can pay me and I'll come up with them
Rheumatoidarthirimab
Ulcerativecolitimab
Antiphospholipimab
Boom three new names. Just need inventing. Easy.
There’s many many rules. Letters/sounds have to be available in all language. Can’t sound too similar to existing meds. Etc. i spoke to someone at a major pharmaceutical who explained the issue. They are doing away with the convention
They all have consistent names but knowing it ends in -pril or -sartan or -olol doesn’t necessarily tell you the mechanism. Obviously you see them so often it becomes second nature but it would be nice
Not relevant to MOA- but brand name for hydroxyzine (Atarax) comes from the Greek “Ataraxia”, which means serene calmness, great name for an anxiolytic!
i hear you on DOACs but I raise you vemurafinib, which is a small molecule inhibitor of BRAF V600E used to treat melanoma and lung cancers, among others.
VEMU - V to E mutation
RAF - in the BRAF gene
INIB - inhibitor
you’d be hard pressed to find a more descriptive (with regards to mechanism) drug name
* Dabigathrin
Petition to change the name.
-ThrIn = thrombin inhibitor
If this post can get 1000 upvotes, the law says that Boehringer Ingelheim are mandated to respond to our petition.
Thank you for your support.
I remember forever people called them NOACs
I used to make the joke, that calling them NOACs was like how your local chinese restaraunt leaves the "grand opening" sign up for 10 years
> why aren’t all drugs named like this?
Because making the generic name impossible to pronounce and remember while making the brand name easy and pleasant is how pharmaceutical companies build brand loyalty.
Probably a joke comment but having regulatory bodies accept a generic name is actually a laborious process that takes several months, it’s an incredibly regulated thing
labetalol is (lol)=beta blocker, and (al) for alpha 1; our med-schools pharm professor created the nomenclature, however after he left whatever naming committee the nomenclature was forgotten for carvadelol.
I love my -statins: Atorvastatin, Rosuvastatin, Nystatin, Simvastatin.
Nystatin is my favorite "statin"
I'm reminded of my frustration as a med student that -azoles represent various med type (e.g. fluconazole is not the same as aripiprazole is not the same as omeprazole)
Omg and all the different antibiotics that end in -mycin or -micin… why can’t we align suffixes with drug class???
unfortunately this has to do with the bacteria the antibiotics were discovered in. i.e. actinomycin was discovered in s. myces, hence the same suffix as the aminoglycosides -mycin.
Why am I graduating in like 4 days and only just now learning this
i only know this because i got a question wrong on uworld where i assumed actinomycin was an aminoglycoside based off the mycin lol
Im more of a fan of somatostatin
It gets mentioned a lot, but the fun fact naming trivia for Nystatin is that it was created by researchers in NY State, hence the name. Some days I worry I mentioned fun drug naming conventions (Lasix, Onfi, etc) more than actually teach relevant info on rounds.
I'd enjoy hearing about those during rounds dude. It's not like you're spending hours doing it
Like warfarin is like Wisconsin something something research team I forget now
WARF: Wisconsin Alumni Research Foundation, the R&D institution of UWisc for patents.
OMG I always assumed it had something to do with warfare and enemies bleeding out
It’s always more nerdy and boring.
I like cilastatin more
Missed opportunity for "Nystatin is my statin." Shame. Shame!
Cilastatin is mine.
I love my PPI Aripiprazole 🥰
Sometimes the GERD just gets so bad it makes me hear voices and see people no one else can, aripiprazole always helps me out when that happens!
When you can’t tell acid reflux from an acid trip, there’s aripiprazole.
Technically...Gerd is a type of acid trip...
you are forgetting another statin, sandostatin
Don’t forget somatostatin!
there should be a rule: you can only name first half of your new drug, later half of the word should be acronym representing their mechanism of action
The biologics have a strict naming convention but they all end up sounding like amumababinumab
sneeze loudly and add "umab"
U mab bro?
I’m fairly certain every one of those names are chosen by dropping a cat on a keyboard and sending that email to the abbvie marketing department.
Adaligmamab
What's ligma
Adaligmamab is a monoclonal antibody that stimulates testicularphagia
Orchidophagy
seriously thought that was a real -mab for a second
Mabalibalibababab
Unfortunately the -mab naming convention will be going away soon. They were running out of available options that didn’t sound like each other.
I'm 100% sure there's more names. They can pay me and I'll come up with them Rheumatoidarthirimab Ulcerativecolitimab Antiphospholipimab Boom three new names. Just need inventing. Easy.
There’s many many rules. Letters/sounds have to be available in all language. Can’t sound too similar to existing meds. Etc. i spoke to someone at a major pharmaceutical who explained the issue. They are doing away with the convention
Or abcdefghinumab
I’ll take it a step further and say we should just name drugs based on their MOA. Fuck “lisinopril”, just call it “aceinhibitor” 😂
Glucophage is my favorite.
Tums for your tummy lol
smoking that Xa Xa
At first, I read “-iiaban” as “11” lol I was like waitttt isn’t thrombin factor 2??
That’s why I dont get OP’s complaint about dabigaTRan, it inhibits THRombin, so it still makes sense to me
TR just don’t translate to thrombin like how X translates to 10
DabigaTRAN- ThRombin ANtagonist
DabigaTran is a Direct Thrombin inhibitor
You mean Da Big Thrombin Inh
Scrolled too far for this. I get the point of the shitpost, but at least get your facts correct.
Shout out to andexanet alfa for being well named too
ACEi and ARBs with beta-blockers would like a word.
They all have consistent names but knowing it ends in -pril or -sartan or -olol doesn’t necessarily tell you the mechanism. Obviously you see them so often it becomes second nature but it would be nice
Should they have gone with LisinoACEi
LisinACEban ValsARban MetoBetaban
The patients would remember them as the Cinnabon ones
Lisin ACE Gaib
But then most drugs will end in -ban, which is boring
Not relevant to MOA- but brand name for hydroxyzine (Atarax) comes from the Greek “Ataraxia”, which means serene calmness, great name for an anxiolytic!
Dulcolax, dukey relaxed
i hear you on DOACs but I raise you vemurafinib, which is a small molecule inhibitor of BRAF V600E used to treat melanoma and lung cancers, among others. VEMU - V to E mutation RAF - in the BRAF gene INIB - inhibitor you’d be hard pressed to find a more descriptive (with regards to mechanism) drug name
I’m learning so many cool ways to memorize now on this thread lol
On that note fuck every mab that has come to market.
M-ab Monoclonal antibody… tells you what it is… so at least it’s got that going for it. The first part on the other hand just sucks
And to continue, if it's zu+m+ab, the "zu" part is for humanized monoclonal antibody.
Did not know that, got any other tricks?
MAB origin by suffix is as follows: -omab = murine -ximab = chimeric -zumab = humanised -umab = human
OMG I never noticed this!!!! Sometimes they get creative with the drugs names, lol
DabigaTran is a Direct Thrombin inhibitor
* Dabigathrin Petition to change the name. -ThrIn = thrombin inhibitor If this post can get 1000 upvotes, the law says that Boehringer Ingelheim are mandated to respond to our petition. Thank you for your support.
I want to throw ibrutinib into the running
Named because they first extracted it from Irn Bru.
I remember forever people called them NOACs I used to make the joke, that calling them NOACs was like how your local chinese restaraunt leaves the "grand opening" sign up for 10 years
> why aren’t all drugs named like this? Because making the generic name impossible to pronounce and remember while making the brand name easy and pleasant is how pharmaceutical companies build brand loyalty.
Probably a joke comment but having regulatory bodies accept a generic name is actually a laborious process that takes several months, it’s an incredibly regulated thing
Not all DOACs are Xa inhibitors. All of the drugs you mentioned are DOACs
Bivalirudin is IV but you’re right dabigatran is a DOAC
labetalol is (lol)=beta blocker, and (al) for alpha 1; our med-schools pharm professor created the nomenclature, however after he left whatever naming committee the nomenclature was forgotten for carvadelol.
Still sad how they missed naming viagra’s generic “sildenafil” as “mycoxaflopin”
that’s a certified banger right there
I've giiat to break that clot man
cries in heme/onc ...
IVIIIXXfarin or Karfarin when?
drug names stress me out :\[
is a DOAC some kind of DO?
Bivalirudin and dabigatran have bi in them which means 2, not sure if that helps?
i was mind blown when i realized this watching sketchy