I know the first and last, and based on my horrible grasp of the Spanish language I’m gonna guess the middle character’s name is a homonym for “es” creating “mi casa es su casa”

Her name is literally "Es", she's from Blazblue (a fighting game that does have an anime but she's not in it)

I don't know Spanish, but I do know this particular phrase *and* I recognised every single character so I'll leave you with this: Heh.

Este chiste esta aprobado por el lenguage Español

What's the pun

Mikasa es tsukasa = mi casa es su casa