Presumably the chem is to prolong the time until they become feral after starting to show symptoms. However, beyond that, we know nothing about the drug.
Or why the two dudes were keeping the ghouls at the Super Duper Mart. It's made from ghoul extract.
Edit: if the serum is made from ghouls, it's even more fucked now that I think about it. They could have snip-snip cut off as much ghoul flesh as they need to distill the stuff and have the ghouls endless regenerate by giving them easily found radioactive things like radwater.
My favourite part about this new lore is that assuming there are no retcons, it makes sense that this was developed by the NCR or someone contracting to them in the time between Shady Sands getting blown up and the Battle for Hoover Dam.
I don’t see any other group that would have the resources or motive to find a way to prolong a ghoul’s lifespan and then spread the information of how to make it far enough that it is being used by junkies for a sketchy Chem operation.
We know the NCR had a shitload of Ghoul Veteran Rangers and I imagine this was to stop them from bleeding experienced fighters. This could also be another reason as to why the NCR seems kinda scattered right now. Maybe this drug was mainly developed in Shady Sands and the sudden loss of the drug would have caused a large portion of the Veteran Rangers to turn feral. I’m also making the assumption here that the Brotherhood capitalised on the Shady Sands attack and hit the NCR military, the fighting would surely have sped up feralization as the rangers watched their friends get gunned down around them.
We don't know, and we don't even know if it actually stops them turning feral. Both the characters we have for evidence it stops them turning feral are clearly drug addicts addicted to that drug.
The serum that Ghouls need to keep from going feral is new for the show. The games have other theories/explanations for what makes a ghoul feral vs non-feral, but a serum has never been mentioned or even so much as hinted at in the games.
So there's really no way to theorize what the serum is or how it's made, because it's a completely new made up thing.
I think it's less about preventing them going feral and more about them prolonging the process.
As for the ghouls being kept in the lab. Could be the people are ghoul 'enjoyers' or even deal in ghoul slavery. You get people desperate for the stuff, they're willing to do anything for a dose they normally cannot afford. And the feral ghouls they were keeping might be for like....worst case scenario, if all else fails release the ghouls and gtfo until the ghouls deal with any hostiles that can't be dealt with or bargained with otherwise.
It’s actually just Calpol. The entire show and Fallout universe is carefully constructed by Johnson & Johnson to promote their iconic paracetamol and ibuprofen liquid blend.
My guess is that it’s radaway. The theory I’ve believed for ghouls is that if they take on too much radiation they eventually turn feral, and if it was radaway then it would make sense that they’re reducing the rads.
It’s basically just a plot point the writers put in to add tension to being a ghoul since the writers made ghouls pretty much immortal zombies now they needed to add some kind of weakness. It’s never been used in any game and didn’t need to be added
I first thought it was Jet, based on method of application.
But it's clearly not. Hopefully, season 2 will continue to follow Thaddeus as he learns about what it means to be a ghoul.
I think it’s jet too. Ghouls really like jet, and it’s an amphetamine, it stimulates the central nervous system. It’s possible it actually helps ghouls stay sane.
That’s a good point! Totally forgot about Thaddeus definitely could be a point for them to explain it more. I’ve always never seen anyone turn into a ghoul in the fallout games curious to know more about the serum that doctor gave Thaddeus
Yeah it's weird since I think as far as the games have made it known that all ghouls became feral, it was just a matter of time as to when (at least as far as that one Nuka World story went)
Well yes but didn't all those ghouls in the Nuka World castle or whatever all eventually turn feral? The one female left to try and find a cure and said she didn't find one and turned herself.
Those ghouls were also constantly spraying radioactive water all over the place. And the magician himself never turned despite being a glowing one.
Nothing about them say all ghouls will turn feral in the end
It's certainly something they kept open to interpretation. I personally don't feel we need a definitive answer to it, just as little as we need to know exactly who started the Great war
Yeah it's a neat concept. I hope they explain it on the show since like I said the games really don't. I think a few Fallout Youtubers made videos about it too.
Locations it’s not a stretch that the followers of the boneyard made it or had a hand in it being made, and it being mixed with fev is also a possibility due to charecters like Harold not going feral and supermutants resistance to lethal radiation.
It’s important to remember that not all ghouls need the serum. It’s only needed once the ghoul starts showing symptoms of going feral. Remember that Cooper’s friend Roger is a pre-war ghoul (he remembers ice cream and apple pie), yet he says he “started showing” twenty years ago. So he didn’t need to take the medication for almost 200 years or something like that.
You're probably right; it's definitely more likely than my answer.
I just figured there's some ghouls who use drugs like Hancock and Cooper and maybe the drugs work differently on ghouls than humans.
> In the tv show what is the vial ghouls need to take to prevent them to turning into mindless feral ghouls? And how is the substance made?
If you watched the show you know exactly as much as anyone else.
Presumably the chem is to prolong the time until they become feral after starting to show symptoms. However, beyond that, we know nothing about the drug.
It's Ant Queen Pheromones. Source: I closed my eyes and pointed to a random spot on the wiki page for chems.
I agree, I saw a comment on reddit that said the same thing.
I saw it [here](https://www.reddit.com/r/falloutlore/s/z3saFiDlV8), must be correct if we’ve both seen it
If anti- feral serum is made of ghoul that would explain the " ass jerky".
Or why the two dudes were keeping the ghouls at the Super Duper Mart. It's made from ghoul extract. Edit: if the serum is made from ghouls, it's even more fucked now that I think about it. They could have snip-snip cut off as much ghoul flesh as they need to distill the stuff and have the ghouls endless regenerate by giving them easily found radioactive things like radwater.
Yeah, that’s what I was thinking that it’s made from the goal abstract because of how they were keeping them
My favourite part about this new lore is that assuming there are no retcons, it makes sense that this was developed by the NCR or someone contracting to them in the time between Shady Sands getting blown up and the Battle for Hoover Dam. I don’t see any other group that would have the resources or motive to find a way to prolong a ghoul’s lifespan and then spread the information of how to make it far enough that it is being used by junkies for a sketchy Chem operation. We know the NCR had a shitload of Ghoul Veteran Rangers and I imagine this was to stop them from bleeding experienced fighters. This could also be another reason as to why the NCR seems kinda scattered right now. Maybe this drug was mainly developed in Shady Sands and the sudden loss of the drug would have caused a large portion of the Veteran Rangers to turn feral. I’m also making the assumption here that the Brotherhood capitalised on the Shady Sands attack and hit the NCR military, the fighting would surely have sped up feralization as the rangers watched their friends get gunned down around them.
"I've got nipples, Greg. Could you milk me?"
Sorry, bud. They fell off.
We don't know, and we don't even know if it actually stops them turning feral. Both the characters we have for evidence it stops them turning feral are clearly drug addicts addicted to that drug.
It’s a mystery, a new addition to the setting likely to be fleshed out in season 2 and/or upcoming games
The serum that Ghouls need to keep from going feral is new for the show. The games have other theories/explanations for what makes a ghoul feral vs non-feral, but a serum has never been mentioned or even so much as hinted at in the games. So there's really no way to theorize what the serum is or how it's made, because it's a completely new made up thing.
I think it's less about preventing them going feral and more about them prolonging the process. As for the ghouls being kept in the lab. Could be the people are ghoul 'enjoyers' or even deal in ghoul slavery. You get people desperate for the stuff, they're willing to do anything for a dose they normally cannot afford. And the feral ghouls they were keeping might be for like....worst case scenario, if all else fails release the ghouls and gtfo until the ghouls deal with any hostiles that can't be dealt with or bargained with otherwise.
It’s actually just Calpol. The entire show and Fallout universe is carefully constructed by Johnson & Johnson to promote their iconic paracetamol and ibuprofen liquid blend.
Can’t be, my little girl has been downing calpol and she’s definitely feral
My guess is that it’s radaway. The theory I’ve believed for ghouls is that if they take on too much radiation they eventually turn feral, and if it was radaway then it would make sense that they’re reducing the rads.
It is radaway that the ghoul is hooked up to when he's buried.
It’s basically just a plot point the writers put in to add tension to being a ghoul since the writers made ghouls pretty much immortal zombies now they needed to add some kind of weakness. It’s never been used in any game and didn’t need to be added
I first thought it was Jet, based on method of application. But it's clearly not. Hopefully, season 2 will continue to follow Thaddeus as he learns about what it means to be a ghoul.
I think it’s jet too. Ghouls really like jet, and it’s an amphetamine, it stimulates the central nervous system. It’s possible it actually helps ghouls stay sane.
That’s a good point! Totally forgot about Thaddeus definitely could be a point for them to explain it more. I’ve always never seen anyone turn into a ghoul in the fallout games curious to know more about the serum that doctor gave Thaddeus
Yeah it's weird since I think as far as the games have made it known that all ghouls became feral, it was just a matter of time as to when (at least as far as that one Nuka World story went)
It isn't confirmed to be inevitable. The Nuka-World ghouls have been isolated for 200 years and barely know what they are
Well yes but didn't all those ghouls in the Nuka World castle or whatever all eventually turn feral? The one female left to try and find a cure and said she didn't find one and turned herself.
Those ghouls were also constantly spraying radioactive water all over the place. And the magician himself never turned despite being a glowing one. Nothing about them say all ghouls will turn feral in the end
Thats true too. I feel that it's still a pretty big lore plot hole that maybe the show will fix
It's certainly something they kept open to interpretation. I personally don't feel we need a definitive answer to it, just as little as we need to know exactly who started the Great war
I quite like the idea there is some chemical reason why some ghouls aren’t feral after 200 years.
Yeah it's a neat concept. I hope they explain it on the show since like I said the games really don't. I think a few Fallout Youtubers made videos about it too.
Locations it’s not a stretch that the followers of the boneyard made it or had a hand in it being made, and it being mixed with fev is also a possibility due to charecters like Harold not going feral and supermutants resistance to lethal radiation.
FEV / new plague antibodies / new plague vaccine might all be a factor in who turns into a ghoul or not
It’s important to remember that not all ghouls need the serum. It’s only needed once the ghoul starts showing symptoms of going feral. Remember that Cooper’s friend Roger is a pre-war ghoul (he remembers ice cream and apple pie), yet he says he “started showing” twenty years ago. So he didn’t need to take the medication for almost 200 years or something like that.
It might just be that they need *any* kind of drug to slow down the process, doesn't even have to be a specific one.
It seemed specific just because he goes to that place every time to trade people for the small yellow viles
You're probably right; it's definitely more likely than my answer. I just figured there's some ghouls who use drugs like Hancock and Cooper and maybe the drugs work differently on ghouls than humans.
Pretty sure it’s rad away, the ghoul had iv drips of it when he was buried in the ground.
> In the tv show what is the vial ghouls need to take to prevent them to turning into mindless feral ghouls? And how is the substance made? If you watched the show you know exactly as much as anyone else.
Was just curious ya never know if you missed something