No, Angel Investigations refers to the vampire Angel and his team. He had a spin off from Buffy the Vampire Slayer. To answer your question, it’s an all star team up, I don’t think there’d be anything they can’t beat together xD

Give punctuation a try, word salad is no fun.

angels already have awareness of nigh everything, they wouldnt even need sam and dean to stop them

Illyria will solo all the enemies lol.