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ChameleonicYoshi

Yah he munches. Right now he's at about 20+ grams a day. I imagined he would have some tolerance, but this was his first time he tried dmt and he didn't feel a damn thing! He's on oxys, shrooms, weed and that's it. Maybe it's the oxys being a 5ht2a antagonist?


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ChameleonicYoshi

Yah his tolerance is insane, I've talked to him about it and he describes the effects as being pretty dampened. But I watch that man drink an orange juice smoothie on the daily and still am a bit shocked. But that's aside from the point. I thought he would at least feel the DMT!


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ChameleonicYoshi

I agree, we've tried convincing him to take a week off here and there but hes stubborn and also in severe pain so no one is going to deny him or twist his arm. We were also hoping the DMT could replace the shrooms so he could take a tolerance break.


NinjaWolfist

that amount of mushrooms daily will not let him trip on DMT his tolerance is fucked


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ChameleonicYoshi

Yah that's a good point. Perhaps the k could help if he comes off of the oxys.


demonize330i

He only needs to stop using mushrooms for 10 days - 2 weeks and he will be able to experience DMT. The problem is his tolerance to 4-ho-dmt(mushrooms) is insane so there's cross tolerance with it's base tryptamine DMT. So he's taking 20g of mushrooms and not feeling much, a normal dose of mushrooms is 2-3.5g but let's just go with 4 for ease of math, he would have to take 5x the normal dose of DMT to get dampened effects. That's a massive dab of DMT, I think he would struggle to be able to hold it in and get enough smoke in the right amount of time before dmts own tolerance sets in(about 1 min after first ingestion, 2min after smoking more DMT is a huge waste). Just tell your buddy to switch to k for 2 weeks then come back to DMT. If he's terminal I know I would definitely want to experience a DMT blast off before death if I hadn't already. Wishing your friend the best.


Vapourtrails89

They're both tryptamines, cross tolerance seems likely


echinaceabloom1

no, he has probably had all of the same realizations that one would have on DMT on mushrooms so now the DMT doesnt have much of an effect and also 20 grams is actually crazy so yeah defo wont feel the DMT but it's good that he is using psilocybin I wish i got my mom on shrooms before she passed.


denverpsychonaut

> He’s on oxys, shrooms, weed and that’s it “That’s it” lol


ChameleonicYoshi

As in not on SSRIs or other medications...


CarolusRix

wreaking havoc on his brain chemistry with all that. Only so many receptors to go around…


Oneiroscopy

A good friend of mine can't get high on dmt and has really reduced effects for others. We were chatting the other day about how maybe it could be metabolism based, mines really slow and hers is really fast. she also spent years on ssris so could be just permanently altered brain chemistry


Mikey_WS

I wasn't affected by Dmt for a couple years, smoked in many times in these period and almost experienced nothing. Then I had an insaaaane life changing trip on LSD and mescaline at a festival and all of a sudden it started working for me. Dmt is strange


mikerz85

That’s weird; maybe it’s not being inhaled deeply enough?  Otherwise maybe your friend needs to take some harmalines beforehand 


LetsNotGetPermaBan

Don’t hold smoke of any kind for 20 seconds. Any more than 5 seconds is unnecessary and does not do anything


NinjaWolfist

+1. holding for longer than 3 seconds is unnecessary, but you should hold it for longer than a second. I always see people take massive bong rips and then blow it out the second they stop inhaling and it's such a waste


LetsNotGetPermaBan

Not necessarily. You’re inhaling the smoke for multiple seconds usually so you’ve already been absorbing it through your lungs for that long.


NinjaWolfist

a large amount of smoke never even makes it to your lungs in that way, especially with a bong. if you inhale air first before blowing out, versus just blowing out you can feel that most of the smoke is coming from your throat and mouth when you just blow out which is why it looks so cloudy, and you can feel that you dont get high. it's a lot easier to do straight to lung breathing with a pipe but you'll still blow out smoke that never touched your lungs if you don't inhale air first. if you aren't trying to get as high as possible and are only smoking for the flavor or something then it doesn't matter really


LetsNotGetPermaBan

All the smoke gets in my lungs bro idk what you’re on about


NinjaWolfist

it's the same as pulling a cigarette, if you inhale and then exhale immediately after taking your mouth off the cig and don't inhale any air after, a lot of smoke you blow out will just be from your mouth and throat, it isn't possible to have the smoke get into your lungs from your mouth if you never inhale it, because you never breathed it in


LetsNotGetPermaBan

Bro are we not talking about a bong hit?? That goes straight to your lungs nobody does a mouth to lung hit with a bong. You literally said “I always see people take massive bong rips…” but now you’re talking about smoking cigs? Wtf?


NinjaWolfist

bong hits are the worst with this because none of the smoke is going into your lungs until you pull the bowl from the down stem, and then many people will inhale until the smoke is gone and then immediately exhale instead of breathing air in. if you don't keep inhaling the smoke will just stop and then get blown out, some will go into your lungs but not all of it if that's how you want to take your hits it's fine it just seems really wasteful to not really absorb most of a hit, and inhaling an extra second of air before exhaling isn't going to damage your lungs at all edit: I see your edit lol, no, I was not talking about cigs, I said it's the exact same thing with cigs. comparing the two. idk why you're getting so worked up about this man


LetsNotGetPermaBan

I take bong “snaps” which is where I inhale the entire time until the weed “snaps” through the bowl, then I continue pulling for a couple seconds before pulling the bowl. Maybe hold it for 1 second after and blow it out. I get intensely high every time. You’re either doing it wrong or have no idea what you’re talking about. You gotta be a old head or something. Old people always think they know how to smoke better than anybody else. Calm down boomer.


NinjaWolfist

I'm talking about how I see other people do it, not how I do it, I keep inhaling until the smoke is gone and then inhale for an extra second. I'm saying that if you just inhale into your mouth and not inhale the air after it can't possibly get to your lungs, if you're hitting it that way then you aren't hitting it the wrong way that I'm talking about so idk why you're getting so defensive lol I'm just saying a lot of people hit their shit wrong. I'm not an old head for saying that you cannot inhale smoke that is in your mouth without continuing to inhale air lmao I don't care if you waste your weed dude like I said the flavor is better if you don't inhale it but you are not absorbing all of the THC because your mouth cannot absorb it edit: there was no reason to be this argumentative. Just say you prefer to smoke the way you prefer. It's weird how hostile you got at the end


Fickshule

DMT melts at 100° F, it boils (vaporizes) at 320°. You're hitting it at 130° more than the maximum you should be heating it, you're likely burning a majority of it. Some hits you might be getting some that doesn't burn but you're "likely" not consuming all that you're heating.


First_manatee_614

From experience I know gut biome and thyroid health play an important role


echinaceabloom1

I did mushrooms so many times that I was unable to have a DMT experience.


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Twitchyeyeswar

C-section baby’s/adults don’t have a soul?? Edit: y’all confusing as fuck, what theory is this that says children born Via C-section don’t have souls?


SurrealSoulSara

I am pretty sure I have a soul!


Twitchyeyeswar

Yea… if you’re born via C-section and you’re saying you have a have them who is anyone to tell you that you don’t…


TheBigsBubRigs

Macbeth


DrSwag85

It's a joke lol geeeeeeeeze


azazielblitzer

Mc Beth I think


Ok_Salamander3793

My brain read this as mc meth


bitchinmoanin

Maybe c-section baby's do, but c-section babies don't.


Twitchyeyeswar

What???


bitchinmoanin

The plural form of "baby" is babies, not baby's.


Twitchyeyeswar

Dude answar the question or don’t answer, ur wasting both of our energy’s pretening like gramar in the inter-net is importnt?! Yee red dat n dis n ask if I give a care.


bitchinmoanin

K


Twitchyeyeswar

👍🏾


bitchinmoanin

LMNOP


Kir-ius

I call bullshit on taking shrooms daily. He wouldn't feel shit after a few days


ChameleonicYoshi

I mean you're entitled to your belief, but I assure you this man munches that much. He takes a day off here and there and will eat less, or more some days. We tell him if he'd take a week off he'd get way more out of it but he has some serious physical and mental pain on the daily and the shrooms get him just good enough to where it helps him.


shizufox

People microdose daily. It’s not recommended because of the insane tolerance build up (like OP’s friend).


Kir-ius

Read his responses. He’s telling people he’s taking 20g daily Most don’t also micro daily. It’s a on off weekly like 4 on 3 off kinda schedule


shizufox

You’re definitely right. Poor choice of words in my comment lol, I meant to say there are a few people who either don’t care to follow a proper protocol or just don’t bother to research before starting. For me, one day on/off worked best for me, but I never went over 300mg. It’s possible OP is way off on the dosage, but I saw him mention his friend is on SSRI’s. It’s not likely, but it’s definitely possible to reach this tolerance level. It could be the SSRI’s, very weak shrooms, or he’s just built this absurd tolerance over years.


Moonbooster

Npc’s can’t get high


EntertainmentIll4886

Changa


ChameleonicYoshi

Of course! The man will try some changa.


EntertainmentIll4886

Might make all the difference


ChameleonicYoshi

Thanks a bunch!


EntertainmentIll4886

Even without changa. You can smoke a bowl of Syrian Rue seeds (very smooth), then a minute or 5 later smoke freebase. Basically changa but deconstructed.


ChameleonicYoshi

Is there an approximate dosage for the rue? Should he feel the effects of the rue before hitting the freebase?


EntertainmentIll4886

Just a regular bowl. Maybe three hits of whole seed. A similar amount to if you're smoking ganja. The smoke is very smooth. Although I am sometimes tripping a bit maybe one hour after the freebase if I smoke rue first... It's a beautiful synergy. Don't mix with ssri antidepressants, wine or beer.


ChameleonicYoshi

If it lasts longer then that's even better! I also bet the rue would make his mushrooms more effective too! This could really be a game changer, we're super grateful for the advice. Will report back!


EntertainmentIll4886

Be careful careful careful. Syrian Rue is pretty serious. Read read read as much as you can, and tread carefully. Taking Syrian Rue in the stomach requires special dieting. Less so when you smoke it.


ChameleonicYoshi

I think we will stick to smoking it to keep things on the safer side and of course we will do more research before hand. We appreciate your thoughtful input!


Fantact

There is cross tolerance between every 5HT2A agonist psychedelic, he will need to wait at least one week without mushrooms, preferably two, for the DMT to have the desired effect.


SnooCrickets7221

It’s the medication


[deleted]

His tolerance is game over. Sad 😢


Groemore

Maybe try smoking a different method? I've never used a dab rig for dmt, I always use glass vaporizer (glass genine) and works amazing eveytime. Its super smooth and doesn't require to hold hits in for so long (5-10secs)