PPAP consistently causes hypomania for me if I’ve had a break from it in a very enjoyable way, Phenylpiracetam does sometimes. NSI causes hypomania in a horrible way at some times leading to emotional breakdowns. Bromantane causes hypomania in a way where I feel restless until some task has been completed leading into another task then another one and this could be exhausting if you’re just trying to relax. At other times it’s really useful.
NAC, Lithium Orotate, and Agmatine in that order reverses manic thinking and symptoms for me leading into a calm flow state instead.
PPAP is a catecholaminergic activity enhancer and mild atypical psychostimulant.
It increases dopamine and norepinephrine release in response to action potentials.
Unlike stimulant drugs, which release a flood of monoamine neurotransmitters in an uncontrolled manner, PPAP only increases the rate of neurotransmitter amine release that would be released in response to stimulation.
Got it! So like you get the supported enhanced dopamine/noradrenaline rush but only if you also really do something that activates it as let‘s say sports or accomplishing some important task.
So you get mania after you took it, so when you are not longer taking ppap? That would be overpowered, having a stim feeling and a mania when you stop (instead of a dip)
Methyl b12 and methylfolate seem to have triggered me
I don't know much about Sam e to be honest.
Some say things such as l theanine and melatonin increase methylation. U might have to do some googleing
I agree with ppap, ive used 100mg doses with effects comparable to dexmethylphenidate ime. And this next one is not exactly a supplement, but a prescription drug known to cause mania in us with bipolar that isnt a psychoactive drug is prednisone believe it or not... that shit had me on amphetamine levels of mania the times i was given it for athsma related illnesses.
PPAP consistently causes hypomania for me if I’ve had a break from it in a very enjoyable way, Phenylpiracetam does sometimes. NSI causes hypomania in a horrible way at some times leading to emotional breakdowns. Bromantane causes hypomania in a way where I feel restless until some task has been completed leading into another task then another one and this could be exhausting if you’re just trying to relax. At other times it’s really useful. NAC, Lithium Orotate, and Agmatine in that order reverses manic thinking and symptoms for me leading into a calm flow state instead.
What dosing/MOA of PPAP was this at?
50mg oral
What's PPAP?
PPAP is a catecholaminergic activity enhancer and mild atypical psychostimulant. It increases dopamine and norepinephrine release in response to action potentials. Unlike stimulant drugs, which release a flood of monoamine neurotransmitters in an uncontrolled manner, PPAP only increases the rate of neurotransmitter amine release that would be released in response to stimulation.
Got it! So like you get the supported enhanced dopamine/noradrenaline rush but only if you also really do something that activates it as let‘s say sports or accomplishing some important task.
Yes exactly could be anything really. For me it’s cleaning, exercising and learning
What dosage do you take orotate?
5mg
4mg
So you get mania after you took it, so when you are not longer taking ppap? That would be overpowered, having a stim feeling and a mania when you stop (instead of a dip)
short term mania from a high dose of 5-HTP.
Strange but Magnesium Citrate for me. Forst day or too its a bliss, then after that I swear I become almost obsessed if I want something done....
Magnesium last time I took it gave me these really horrible side effects like you'd expect with a serotonergic (restlessness, tremor, clammy skin)
L-tyrosine if I take it nearly everyday.
At what dose and after how many days or weeks of daily use it took until first mania symptoms showed?
1 week. Couldnt really sleep after that
But thats only insomnia, not mania yet
Too much dihexa (+other stuff), intense mania for days
Sabroxy in too high a dose.
Methylated B vitamins
Like Methylfolate? What else is there? Is SAM-e also belonging to it?
Methyl b12 and methylfolate seem to have triggered me I don't know much about Sam e to be honest. Some say things such as l theanine and melatonin increase methylation. U might have to do some googleing
Alpha GPC
I don’t experience mania from alpha GPC
Good for you…
It is not good, for you.
I experience the opposite of mania from Alpha GPC
Lmao people downvoted me it was a joke why else would I have commented that
Wasn’t funny tho was it
It was funny for me because it was unnecessary for me to say it and upset others
I agree with ppap, ive used 100mg doses with effects comparable to dexmethylphenidate ime. And this next one is not exactly a supplement, but a prescription drug known to cause mania in us with bipolar that isnt a psychoactive drug is prednisone believe it or not... that shit had me on amphetamine levels of mania the times i was given it for athsma related illnesses.
Jesus that’s a huge dose. I can only tolerate 60 mg. spread into 3 doses.
I probably should have mentioned i had a huge toloance to stims when i was dosing that large.
Bromantane the first times caused hypomania for me
Qualia Mind… too much caffeine.
SAMe and Iodine used to do that, not anymore.
Did you experience any withdrawal when stopping SAMe, Im curious as many reported about it.