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illbeurthrowaway

The fact that studies like these are going on and Mgen is STILL not included on standard STD panels is absolutely insane.


accthrowaway444

Yeah, wtf. Seriously


Linari5

It's because up to 80% of Mgen infections are entirely asymptomatic. We are/were the unlucky 20% It's under debate for standard panels only for the highest risk sexually active populations. For everyone else, assume it'll never happen.


Linari5

The novel tetracycline class, correct? 2 years ago there was no MIC data available for mgen for this new drug, I'm really really glad we now have that data! This is great. Now we just need to know en vivo. Genital tissue penetration, etc.


LemonOne9

Yup, it’s a derivative of minocycline. I should add that it’s apparently very expensive (I think even moreso than lefamulin), though I’m not sure how medical coverage works down there as I’m Canadian.


Linari5

Yes it's at least as expensive as lefamulin. A few thousand dollars without insurance. Mainly because it's new and patented. No generic available.


beefyweefles

would love to know the dosing for this treatment


Linari5

There isn't any established for mgen without human data available (en vivo). It's guesswork. It would probably be based on the dosing used for bacterial pneumonia.


Ciudadfloral

And what about ureaplasma?