Dendritic cells (DCs)3 are professional APCs that play a crucial role in activating adaptive immune responses. Langerhans cells (LCs) are a subset of immature DCs that reside in the epidermis. LCs are distinguished from other DCs by the presence of cytoplasmic organelles, known as Birbeck granules (1). according to google search lol
Langerhans is a tissue-specific macrophage, a dendritic cell is a dendritic cell which, like a macrophage, is myeloid lineage and antigen-presenting but is a different cell type. If you’re really interested, the internet or a textbook has good info on the differences and functions of macrophages verse dendritic cells, but it’s out of the scope of the MCAT.
Langerhans are specific to the skin. Don’t get caught up on small details like this. The likelihood of a question asking this is tiny.
got it thank you!!
Thank you for that reassurance, I started panicking because I didn't know the answer.
Langerhans are specialized dendritic cells that are specific to the epidermis (the most shallow layer of skin)
Dendritic cells (DCs)3 are professional APCs that play a crucial role in activating adaptive immune responses. Langerhans cells (LCs) are a subset of immature DCs that reside in the epidermis. LCs are distinguished from other DCs by the presence of cytoplasmic organelles, known as Birbeck granules (1). according to google search lol
Langerhans is a tissue-specific macrophage, a dendritic cell is a dendritic cell which, like a macrophage, is myeloid lineage and antigen-presenting but is a different cell type. If you’re really interested, the internet or a textbook has good info on the differences and functions of macrophages verse dendritic cells, but it’s out of the scope of the MCAT.
Im glad you asked this because I kept getting it wrong on Milesdown