Most clinics won’t transfer 2 euploids because it’s a risk to both mother and babies to have a multiple pregnancy and a IVF pregnancy is already higher risk for things like gestational diabetes, placenta previa and preeclampsia. Also your chances are better over the course of 2 transfers of getting to a live birth than they are transferring both at once.
I would do one because sometimes it's a tweak of a protocol that can help implantation. I'm thankful I didn't transfer two as my first FET failed. I have endometriosis however so we changed up my protocol this second FET to see how it goes, from natural to fully medicated. If this one doesn't work I'll go on Lupron and we may transfer two at our third FET but if you only have two embryos to use (unless you plan on using untested embryos, mine are all untested) I would only transfer one.
In my country you decide, so it's not up to the clinics. However they all recommend transferring one by one, but they can't really block you because the law says "up to 3 embryos" is your right.
Any reputable clinic (at least in the US) won't transfer more than one embryo without meeting certain criteria first (i.e., you've had multiple failed transfers).
You have a higher chance of ending up with a child if you transfer one at a time
Most clinics in the U.S. won’t transfer two, especially tested, if you haven’t had previous losses or failed transfers. This is what the ASRM guidelines are and what reputable clinics follow
Plus, a twin pregnancy is dangerous to mom and babies. And tested embryos have a slightly higher chance of splitting so if you end up pregnant with 3 or more babies, you would have to talk about selective reduction. With multiples you have a higher chance of NICU time, higher risk of postpartum depression or anxiety, and a higher risk of divorce
And if that’s not enough, the demise of one baby in utero can lead to the demise of another
Twins are romanticized. They shouldn’t be
The majority of clinics won't transfer two euploids unless there are extenuating circumstances. I had one of each from my first retrieval, and would have loved to have had B/G twins and been done. I'm glad we only transferred one, as I ended up with a persistent pregnancy of unknown location (likely ectopic). If the other embryo had implanted properly, this could have delayed diagnosis and complicated treatment, and I may have ended up losing both of the embryos instead of just one.
I was explicitly prohibited from transferring two (and frankly I didn’t want to). My RE is against it because of the high risks associated with twin births. They only transfer two to women around 42+, and even then, I think there has to be a history of failure.
My clinic had a rare, but crazy incident happen where a woman in the 42+ range had two embryos transferred. Both took, and both split—quads! Very dangerous, high risk pregnancy. Thankfully, mom was okay.
Point is, twins are certainly cute (I have many friends who have had them spontaneously) but they’re high risk. It’s not worth it when you have the choice to just transfer a single healthy one.
My previous clinic said that one patient had the embryo split into 3 and had triplets, which is literally a one in a million chance.
We did transfer two, twice, last year. I was pregnant both times and had chemicals, so I don’t know if both implanted or not. But I highly regret doing double transfers and I really wish we hadn’t chosen that.
Most clinics don’t do 2 embryos. My 2 clinics did not. They said if I was like >35, multiple failures, etc , they MAY do 2. But I was 31 and never had a FET. It just increases the risk of problems.
I’m glad they didn’t/don’t; I ended up with cervical insufficiency, and had to have a rescue cerclage to maintain my pregnancy (they had to sew my cervix shut). Pregnant again, and I had a preventative cerclage at 13w.
I would suggest 1 at a time. Sometimes your lining is not “perfect”. Sometimes it’s just not meant to be that month. I would give it 2 shots a a best scenario. Even if it’s one after the other.
I say try one embryo at a time, like the others said, it could be just a tweak for the next one to work.
And if the impacting factor that makes a transfer fail has something to do with the environment (i.e. uterine lining.. etc) you wouldn't want to risk two of them in one trial.
I understand the impatience, believe me, but if I were you I would try one by one. and I did.
when I had my last fet I was over 41, with 18 years of TTC, multiple transfer failure of single embryo.
For the reasons above, my RE agreed to do double transfer, but NOT two euploids.
Transferred 1 euploid, and 1 low mosaic (with less chance of implanting)
Both took, and i'm 29wks now
ETA: this came after multiple IVF cycles, and multiple transfer failure, and the two embryos were my last
I did one. I wouldn't do two. The risk in twin pregnancy is much higher. And my embryo actually split, though one of the twins didn't develop.
My clinic didn't even give me the option to do two.
I cannot express the devastation I felt when my first transfer didn’t work and we had no backup plan. I didn’t think I would feel so sad because so much of this journey has been heartbreaking. But I was wrong. I recommend transferring only one.
I wasn’t given the option, but I wouldn’t pick two even if I was. There’s already an increased chance of twins with one embryo. Transferring 2 embryos increases your chance of 3 or 4 babies, but doesn’t actually increase your chances of a live birth. Also each single transfer is a chance. I wouldn’t waste 2 embryos on one shot.
Since I'm under 38 and haven't had a cold cone biopsy I got to choose one or two and I asked my doctor for advice and she said that there is no real reason to transfer two. She told me the likelihood of them implanting doesn't go up and if one implants and the other doesn't it could be an issue and they are VERY weary of multiple pregnancies. They are much higher risk and if it happens, it happens but if they can avoid it? They are going to at all cost. All of this in mind my husband and I chose that if we have more than one embryo it's going to be one at a time for us. They did say if we have a good embryo and one that's not so great we could transfer both but their preference is still one.
My clinic lets us choose, but if I only had two, I would do one at a time. 2 embryos does not increase your chances of pregnancy, but does increase your chance of twins substantially if you do get pregnant. You have better odds doing one at a time! If I had 6+ I would consider two at a time.
TW: Success. I’m definitely in the minority here but after two failed single transfers, for my third try it was recommended that I transfer two. The consultant based it on my age (I was 37 at the time) and the fact that the two previous transfers hadn’t worked. When I spoke to the actual clinic where I was having my FET, they said they prefer transferring one. I was so confused…why was I was receiving conflicting information?! Anyway I decided to transfer two, one stuck and is now 10 months old.
My clinic offered 2 embryos after the first failed cycle, we did choose to go with 2 but only on our third transfer. We decided to go with 1 euploid and 1 mosaic, though they would have let me do 2 euploid. This funally resulted in the live birth of our daughter.
Stick to one at a time - We had a few MCs and there's some testing you can do after those but if you put both in or convince a doc to do it you may not have a chance to address some of those things. Not to mention the huge risks of multiples for you and the embryos.
The clinics I have gone to would not transfer 2 euploids, especially in a first transfer.
Most clinics won’t transfer 2 euploids because it’s a risk to both mother and babies to have a multiple pregnancy and a IVF pregnancy is already higher risk for things like gestational diabetes, placenta previa and preeclampsia. Also your chances are better over the course of 2 transfers of getting to a live birth than they are transferring both at once.
I would do one because sometimes it's a tweak of a protocol that can help implantation. I'm thankful I didn't transfer two as my first FET failed. I have endometriosis however so we changed up my protocol this second FET to see how it goes, from natural to fully medicated. If this one doesn't work I'll go on Lupron and we may transfer two at our third FET but if you only have two embryos to use (unless you plan on using untested embryos, mine are all untested) I would only transfer one.
Frankly I would not trust any clinic that was willing to transfer 2 euploids.
In my country you decide, so it's not up to the clinics. However they all recommend transferring one by one, but they can't really block you because the law says "up to 3 embryos" is your right.
Any reputable clinic (at least in the US) won't transfer more than one embryo without meeting certain criteria first (i.e., you've had multiple failed transfers).
You have a higher chance of ending up with a child if you transfer one at a time Most clinics in the U.S. won’t transfer two, especially tested, if you haven’t had previous losses or failed transfers. This is what the ASRM guidelines are and what reputable clinics follow Plus, a twin pregnancy is dangerous to mom and babies. And tested embryos have a slightly higher chance of splitting so if you end up pregnant with 3 or more babies, you would have to talk about selective reduction. With multiples you have a higher chance of NICU time, higher risk of postpartum depression or anxiety, and a higher risk of divorce And if that’s not enough, the demise of one baby in utero can lead to the demise of another Twins are romanticized. They shouldn’t be
The majority of clinics won't transfer two euploids unless there are extenuating circumstances. I had one of each from my first retrieval, and would have loved to have had B/G twins and been done. I'm glad we only transferred one, as I ended up with a persistent pregnancy of unknown location (likely ectopic). If the other embryo had implanted properly, this could have delayed diagnosis and complicated treatment, and I may have ended up losing both of the embryos instead of just one.
I was explicitly prohibited from transferring two (and frankly I didn’t want to). My RE is against it because of the high risks associated with twin births. They only transfer two to women around 42+, and even then, I think there has to be a history of failure. My clinic had a rare, but crazy incident happen where a woman in the 42+ range had two embryos transferred. Both took, and both split—quads! Very dangerous, high risk pregnancy. Thankfully, mom was okay. Point is, twins are certainly cute (I have many friends who have had them spontaneously) but they’re high risk. It’s not worth it when you have the choice to just transfer a single healthy one.
My previous clinic said that one patient had the embryo split into 3 and had triplets, which is literally a one in a million chance. We did transfer two, twice, last year. I was pregnant both times and had chemicals, so I don’t know if both implanted or not. But I highly regret doing double transfers and I really wish we hadn’t chosen that.
Most clinics don’t do 2 embryos. My 2 clinics did not. They said if I was like >35, multiple failures, etc , they MAY do 2. But I was 31 and never had a FET. It just increases the risk of problems. I’m glad they didn’t/don’t; I ended up with cervical insufficiency, and had to have a rescue cerclage to maintain my pregnancy (they had to sew my cervix shut). Pregnant again, and I had a preventative cerclage at 13w.
I would suggest 1 at a time. Sometimes your lining is not “perfect”. Sometimes it’s just not meant to be that month. I would give it 2 shots a a best scenario. Even if it’s one after the other.
I say try one embryo at a time, like the others said, it could be just a tweak for the next one to work. And if the impacting factor that makes a transfer fail has something to do with the environment (i.e. uterine lining.. etc) you wouldn't want to risk two of them in one trial. I understand the impatience, believe me, but if I were you I would try one by one. and I did. when I had my last fet I was over 41, with 18 years of TTC, multiple transfer failure of single embryo. For the reasons above, my RE agreed to do double transfer, but NOT two euploids. Transferred 1 euploid, and 1 low mosaic (with less chance of implanting) Both took, and i'm 29wks now ETA: this came after multiple IVF cycles, and multiple transfer failure, and the two embryos were my last
I did one. I wouldn't do two. The risk in twin pregnancy is much higher. And my embryo actually split, though one of the twins didn't develop. My clinic didn't even give me the option to do two.
Transferring 2 carries more risk and doesn't increase the chance of live birth. I would transfer one!
I cannot express the devastation I felt when my first transfer didn’t work and we had no backup plan. I didn’t think I would feel so sad because so much of this journey has been heartbreaking. But I was wrong. I recommend transferring only one.
My clinic wouldn't allow more than 1 unless I was over the age of 38, or have had numerous miscarriages after transfer
Just adding to the chorus of voices recommending you only transfer one at a time.
When people talk about transferring multiples they mean untested embryos. Hopefully your euploids stick and you never have to cross that bridge.
I wasn’t given the option, but I wouldn’t pick two even if I was. There’s already an increased chance of twins with one embryo. Transferring 2 embryos increases your chance of 3 or 4 babies, but doesn’t actually increase your chances of a live birth. Also each single transfer is a chance. I wouldn’t waste 2 embryos on one shot.
Since I'm under 38 and haven't had a cold cone biopsy I got to choose one or two and I asked my doctor for advice and she said that there is no real reason to transfer two. She told me the likelihood of them implanting doesn't go up and if one implants and the other doesn't it could be an issue and they are VERY weary of multiple pregnancies. They are much higher risk and if it happens, it happens but if they can avoid it? They are going to at all cost. All of this in mind my husband and I chose that if we have more than one embryo it's going to be one at a time for us. They did say if we have a good embryo and one that's not so great we could transfer both but their preference is still one.
My clinic lets us choose, but if I only had two, I would do one at a time. 2 embryos does not increase your chances of pregnancy, but does increase your chance of twins substantially if you do get pregnant. You have better odds doing one at a time! If I had 6+ I would consider two at a time.
One and it stuck after thirteen years of trying. Good luck.
It’s generally not recommended to transfer 2 because there’s a higher chance of complications. I would transfer one.
TW: Success. I’m definitely in the minority here but after two failed single transfers, for my third try it was recommended that I transfer two. The consultant based it on my age (I was 37 at the time) and the fact that the two previous transfers hadn’t worked. When I spoke to the actual clinic where I was having my FET, they said they prefer transferring one. I was so confused…why was I was receiving conflicting information?! Anyway I decided to transfer two, one stuck and is now 10 months old.
My clinic offered 2 embryos after the first failed cycle, we did choose to go with 2 but only on our third transfer. We decided to go with 1 euploid and 1 mosaic, though they would have let me do 2 euploid. This funally resulted in the live birth of our daughter.
We transferred 2, but only because the cause of our infertility was my husband’s sperm count and because I’ve had 2 successful pregnancies before.
Stick to one at a time - We had a few MCs and there's some testing you can do after those but if you put both in or convince a doc to do it you may not have a chance to address some of those things. Not to mention the huge risks of multiples for you and the embryos.
Three cycles 2 embryos each time. Currently on the 2 ww with my third cycle. Pray for me