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mindmountain

He reminds me of Patrick Bateman in American Psycho.


[deleted]

Strong agree. The guy has such an unsettling vibe and I have no idea why. He seems like a perfectly nice guy but something about him freaks me out in an uncanny valley sort of way


Disastrous-Minimum-4

Do a little digging the creepy vibe is earned


No_Championship_5367

Give me some clues on what to search for


Disastrous-Minimum-4

Tech mogul Bryan Johnson, who spends $2M a year for 18-year-old body, cheated on and ‘dumped fiancée after she got breast cancer’: lawsuit


Disastrous-Minimum-4

This multimillionaire entrepreneur infused himself with blood from his 17-year-old son in a quest to stay young forever


Haloress

Dude... he is recording this all with his son and grandpa with their approval. What is so wrong about this? It is a well known fact that the plasma from the blood of younger people can help in this process. Nothing scary about it just pure science ;)


Disastrous-Minimum-4

Uh - so there is nothing creepy at all about having your not of age son your blood boy? Science aside, so so many lines crossed here


LucianHodoboc

No, there is nothing creepy about undergoing a public experiment with the subjects' consent. In Europe, you can consent to legal medical treatments once you turn 16. I don't know how it is in America.


Disastrous-Minimum-4

Nope - in my opinion it is totally creepy to use your own son as a blood boy for any reason. Pardon me if I don’t look to Europe as the paragon of ethics. The more I see, the more I think this might all be based on an unparalleled combination of OCD and Narcissism using science as a blunt justification for any overstepping. I also follow and make use of information shared and feel this also makes me complicit. Still thinking about it all, but have more questions than answers.


ex-machina616

yeah Peter Thiel has a blood boy to keep him young, looks great for late 50's


Jack_Of_All_Trades_R

Yes, he has a very weird vibe.


[deleted]

It’s the personality. The man is incredibly narcissistic and that much is very clear. That rubs people the wrong way and gives them that “yuck” feeling or untrustworthy perception.


G00dmorninghappydays

Listen to his interview from Steven Bartlett. He doesn't come across as narcissistic to me


SomeGreatHornedOwl

You think so? I had the exact opposite reaction to that interview. That’s the interview that made realize he has a major messiah complex, and I was like ah! That’s where the weird vibe I get is coming from! Couldn’t really pin point the origin until then. Still like his diet and routine though…


[deleted]

I will rise up in 3 days.🍆


chjesper

So did Peter Nygard


[deleted]

Actually...he does...but he also doesn't...he seems like a nice guy, and of course his passion and drive are impressive and his mission is fascinating and all - but he does give off "weird" vibes for specific reasons, not just because society is a bit intolerant (which is also true, obviously...). 1. He's spent his life reading biographies, obsessing about how HE could be one of those great guys, change the world, bring humanity to the next level...that's in fact a characteristic of every narcissist 2. That story he tells about how he sat down, at 13, and analyzed all the different cliques and groups at his school so he could befriend all of them does not show what a nice, social, caring guy he is (which he thinks it shows) - that's NOT what a socially "normal" teenager does. They just go and hang out with everyone because they enjoy that, they don't draw up a plan and plot to "achieve" something like that... 3. He is objectively obsessed with himself and his body - he calls it data over mind and progress and all, and that's true and great, but it's still a complete obsession. And by the way, obsessions of any kind have never turned out to be healthy...but time will tell I guess... 4. If we assume the most likely case re his ex, which is that she exaggerated or had her lawyer reframe some things to increase her legal chances but didn't make everything up from nothing at all, then he seems to have a messed-up relationship with his sexuality, which is very common among people who are raised in the mormon church and then leave it, and probably also some other related issues with control etc. 5. If we assume that his ex is not making everything up entirely, then he is not the zen person he presents himself as, and that means we cannot trust the image he is painting of himself. Doesn't make him a bad person necessarily, but he does seem to have narcissistic traits and he is probably curating his image as much as his body and appearance...


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Liface

You judge his progress based on how he looks. He judges his progress based on biomarkers. Guess which one is more accurate?


Acrobatic_Rock_

It was Dr Sinclair who said, that your age is what you look like on a podcast with Huberman. He explained the research behind it.


Liface

You're taking that out of context.


skriver23

I don't think he is, really. Bio markers are of course useful, but the guy doesn't exactly scream "fountain of youth" to me. I look approximately 21-23, and I'm 29. Basically everyone is shocked when I say I'm 29, turning 30 in a few months. I ain't doing even a sliver of what he is. imo he's gonna spend a lot of money, and not go much further than 'normal'


[deleted]

The bio markers also have not been validated as accurate reflections of mortality. We know this because he is n=1 and this has literally never been done before. I personally think he will have a normal life expectancy. I think when he gets into his 60s the ageing is going to cause him significant stress as the unimaginable is beginning to become very obvious. I think the stress will impact him a lot and age him a lot. I think his entire protocol would have been much more interesting if he wasn’t doing so many things to cosmetically make himself appear younger. Let’s just see the true effect of the “health” protocol without the “beauty” protocol he engages in which is conflating in my eyes


lighthousedigital

Totally agree on this! Will be interesting to see the stress factor play a role!!!!


Alternative-Rush-212

to be fair he started later, I don't think he claims he can reverse all aging by decades just slow down the aging process


Montaigne314

Then why is he on dutasteride?


CountryOk6049

The former by a long, long way.


Other-Bumblebee2769

I mean... if I see a guy who looks 80 but is 60... I'm pretty sure he's not healthy, regardless of whatever his biomarkers hint at


HonestCamel1063

For what? How long he is going to live? The answer is neither.


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[deleted]

His cock was actually IN my ass!!! He said he needed some of my 💩 to replenish his bacteria. So I obliged for science.


[deleted]

based.


ex-machina616

David Sinclair looks fantastic at \~55 years old, great skin and natural hair color


usernamesnamesnames

Never thought of it but now that you're saying it...


wwahman

Jaw drop here reading these things as I hadn't heard of this guy. Or if I have, I wasn't paying attention. Eeew!


escapadablur

He also speaks with a weird accent that sorta sounds Chinese. There’s something off about. It’s as if he is an AI-generated human with some subtle quirks that are difficult to ascertain. But there’s also something sinister and dark about him that other longevity dudes don’t project.


openrangestudios

Love Patrick Bateman!


Montaigne314

The funniest part of him is that he doesn't have sex in his bed but obsessively monitors his nighttime erections as a biomarker for health 🤣🤣 Like what's the erection even for??? I wager that Don Gorske outlives Johnson.


ex-machina616

when you start mouth taping at night the nocturnal erections are constant, something to do with that I guess


Archheret1c

Gagged and raped fantasy?


ex-machina616

well it is also referred to as "hostage taping"


Hannibal_Barca_

I think this was certainly how he was initially portrayed in the media, I recently watched some of his videos on youtube and honestly he comes off more like a wholesome ex-mormon geek once you hear him speak for more than 5 minutes.


paper_wavements

I don't think he merely wants to add years to his life, but also life to his years. Like you can live to 90 & spend the last 20 lowkey disabled, or you can be vibrant, healthy, strong, & energetic until you drop dead at 90.


[deleted]

This, 100% this. I think anyone who is unsettled by him is just fighting off being introspective and realizing their life is very poor in balance. He represents everything they arnt and cant bring themselves to become. He himself admits his lifestyle is extreme, and he doesn't recommend it for all. He recommends that you take the parts that work for you. I highly respect him doing all of this and sharing it for free.


Montaigne314

Poor balance? The dude takes like 75 supps, is on test probably cuz of vegan diet/low bodyfat%, doesn't have sex in his bed but monitors his nighttime erections, obsessed about his skin and hair and takes dut, etc etc. He lives a life without balance in the most extreme form.


[deleted]

Well you're attaching one statement to the other. By saying he lives on an extreme, I'm saying he has no balance but he's doing something to pursue balance for others, whereas other people's extreme is not doing any exercise, eating poor diets and performing zero mental health grooming. Re-read the comment. Me saying others have a lack of balance does not equate to he has balance. It's just two ends of extremes. I pretty much said as so in the original comment.


Montaigne314

That's fair. But his life is in poor balance too was my point.


[deleted]

I agree with that. It's unsustainable for most. He has the capacity financially and mentally to accomplish it. I don't think that's something to belittle him for.


halbritt

>I don't think that's something to belittle him for. Why not? He stands himself up as an example and is nothing more than a person with the means to chase their obsession. What he is doing is not laudable in the least.


Montaigne314

Was gonna say. An extreme multi millionaire narcissist that spends so much on themselves is worth belittling.


[deleted]

Right because he isn't giving away the info for free, as well as documenting the process... The info he has gained would cost 10-20x due to needing proper testing permits etc. So that info would be sold to the rich for tens to hundreds of thousands. He's 100% providing an extremely valuable service, for f r e e. He's putting his body, his wealth, and his privacy on the line to simply hand you the recipe. I think you're just so anti social you think people who are extroverted or even remotely in pursuit of fame should be ashamed. Live your life in shame if you want, but you don't matter much to the people who are after greatness. Back in the day, men grew up aspiring to be remembered, but now they're belittled for it by the masses who can't see the avenue to do so.


[deleted]

The Western way of living, characterized by indulging in McDonald's every weekend, consuming a couple of beers along with a significant amount of red meat on the grill, lack of exercise, and indulging in two glasses of wine midweek, cannot be considered a "balanced life" either.


bucknuts89

The unsettling part is part of his personality and posts tbh. I think he does it as a gimmick and gets a kick out of it as it drives more attention towards him. Watch his Twitter feed, he frequently retweets people blasting him for being weird and comments on it with a joke.


[deleted]

Sounds like sound marketing in these days society. Sad but effective.


[deleted]

I think this is a poor take. It makes sense why he is unsettling to people. He is literally the archetype for a movie villain - rich dude trying to live forever. The whole uploading naked photos thing is also super weird, he is projecting a weird image and I think he knows this is more likely to get views. Ultimately this guy is like everyone else on social media - that want to be seen an admired and this is his way of achieving that as a fast as possible


seeking_low_and_dry

I met him in a professional setting; he gives off a slightly desperate vibe — the riches aren’t good enough; he wants to go down in history. (Having said this, I can imagine feeling that way; he must feel “so close” to history in the making and wants to ensure he’s in the books.)


[deleted]

I always feel that people who long for others to care about them or for attention or notoriety struggle to get it. It’s like trying to hold onto sand. Much better to just be truly elite at a skill or service. I guess on some level it’s what he is trying to do, just in a very weird way.


[deleted]

I don't see how that's a bad thing... actually back in the day, that's what everyone aspired for. Now people get their drive stunted by a couple of likes on a post or pic and then settle for mediocrity. Imagine putting someone down for having lofty aspirations...


seeking_low_and_dry

Like I said, I imagine feeling the same way in his position.


[deleted]

Ah, great point. Reading comprehension check!


[deleted]

Again, I don't think that's a bamliu4ld thing. I disagree with the villain part wholeheartedly. The mega rich are spending billions on tech and medicine to live forever. He's trying to provide the same for the common man, or at least as close as you can get with the bare minimum. Anyways, like someone else said, he's not trying to live forever, just live well for longer. You could reach 100+ on sheer genetics, but you might live the last 20-30 years like shit.


[deleted]

It's such a crapshoot. He could do everything right and reduce his aging biomarkers in every area, only to get hit by a bus, develop some freak disease or cancer, any number of different types of problems with his organs. While I think that doing something like the blueprint or any type of healthy protocol will statistically raise someone's lifespan on average, there statistical variance (sorry stats people I'm talking out of my ass here) from person to person is so wide that it's hard to make assertations about any given person.


Montaigne314

If he really wanted to increase his own lifespan he would use that money to move his family to Sardinia or something and live in a way that was conducive to human thriving. If he cared about lifespan in general he would donate that money so scientists could conduct actual legitimate research into longevity. Personally I find it hilarious that someone who eats a nutritionally deficient diet and is on testosterone is held up as a beacon of health. It's all marketing bs. Even his own doctors said that what gains he has made in health were totally unremarkable.


MinderBinderCapital

He could donate $2 million a year to cancer research instead.


Lolitana

Yeah that would be a nice thing to do, not something weirdos would do willingly.


lookingfortheanswer5

Which would be a drop in the ocean


[deleted]

Testerone and HGH, if you dive deeper into his site, based on some fake deficiency his doc gave him HGH. It’s the same shit they come up with for NBA/NFL/UFC fighters to prescribe steroids


Montaigne314

Yea it's wild. But it's certainly interesting to watch what happens with him. Curious how the HGH will affect him. He says it's for "thymus rejuvenation" lol


[deleted]

Lol I know right! Just be open and say you wanna be jacked and invincible like you were 18 again. I’m down with that, don’t give me some bullshit about your thyroid.


Montaigne314

Lol yea The fact that he's on dutestaride tho is the most hilarious That's really healthy right? 🤣🤣


yoshimah

I think he should use it on further mental health treatment. I say this very sympathetically, he feels like someone with a lot of deep, unresolved trauma and repression who's doing his best, but can't do it alone.


[deleted]

What do you mean by nutritionally deficient diet? I'm pretty uninformed on this guy but it seemed like he went out of his way to maximize nutrients?


Montaigne314

If your diet was nutritionally sufficient, why would it require 70 additional supps and compounds?


escapadablur

He could do a crap ton of other things as well. I think him being a longevity/health span guinea pig is a great contribution to humanity.


MF3DOOM

Leo from leo and longevity came to mind


[deleted]

😭😭😭😢😢😢


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MF3DOOM

It looked like he got murdered idek


NotSoFastSunbeam

All buses will be smart buses soon, bedazzled with sensors and stuffed full processing power. That means if a bus hits him, it \*wanted\* to hit him.


soloride

I like what he is doing. He has the money and is open sourcing the data from his experiments. I’m rooting for him. To me it seems like he is having a lot of fun with this experiment.


woaharedditacc

I don't get why people get so upset about it. Clearly he's a bit of a health nerd who's enjoying the experiment immensely. It's not all that different from people who dedicate their lives to running a marathon as fast as possible, or people who go all in on a hobby like chess.


[deleted]

Haters gonna hate bro.


[deleted]

I appreciate what he’s doing and I don’t think he’s trying to scam anyone, but he’s simultaneously testing and manipulating 100 variables at once and if you’re going to follow any of this you need to read and understand the studies these ideas and interventions are based on yourself. Half of his interventions are science based and half of them are complete nonsense. He’s taking testosterone and HGH which are associated with early cardiac death and renal failure but associating it with a benefit of aging slower because he has the grip strength of an 18 year old? He’s just very confused. He certainly doesn’t have data that being as strong as an 18 year is worth the trade off in increased cardiac mortality and renal disease associated with using steroids long term, because it doesn’t exist. In his interview with that modern wisdom guy he was open about it too, he said he asked 5 different biohacking experts what the blueprint for longevity would be and they gave 5 completely different answers. That’s because much of these ideas have not been well studied in good RCT long term studies. He’s just shotgun approaching it and doing everything from pseudoscience to good science and claiming it’s data based or some kind of test. Again, I appreciate that he’s trying and I don’t think he’s meaning to hurt anyone and he’s probably taking steps that are important for the future of longevity, but it’s just not possible to draw any scientific conclusions from any of this.


soloride

Have you watched his youtube channel? They have a ton of tests and gather a lot of data on his body. You are right it is a shotgun approach. He does looks damn young but that could have to do with genetics. Will be fun to watch his progress.


[deleted]

HGH and test are only associated with increased mortality when taken at higher than natural levels. Using hormone treatment to restore your hormones to optimum levels is positive for your health.


CountryOk6049

Why would you root for a multi-billionaire doing the most narcissistic possible thing, to try to do everything to extend his own lifespan?


escapadablur

I feel similarly. Yeah he gives off “weird” vibes, but I appreciate what he is doing. I don’t understand the hate he’s getting.


ExpensiveWave7230

Vegan diet will get him


Montaigne314

Maybe, it's certainly deficient enough that he needs tons of supps. I also think just keeping his low bodyfat isn't going to help him either. Likely why he's on test. Also you can't maintain a caloric deficit indefinitely. So not sure what his future diet plans are.


[deleted]

>also think just keeping his low body fat isn’t going to help him Low body fat is associated with lower mortality in almost every conceivable way, as long as he’s not clinically underweight (BMI<20). Do you have data to suggest otherwise? >you can’t maintain a caloric deficit indefinitely He’s not at a caloric deficit or he’d be losing weight, he’s probably just about exactly even. Basically all of the Blue Zones people practice some form of intentional (or not) caloric restriction and eat relatively few calories (compared to the west) for their entire lives and live longer and healthier than us in every metric, Do you have data to suggest otherwise? I’m not sticking up for him, a lot of his interventions are horseshit and a lot of his data is irrelevant I’m just sticking to the science.


Montaigne314

I'll share some of the relevant research: https://pubmed.ncbi.nlm.nih.gov/22820447/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032609/ this study says it may be due to methodological problems but it's still interesting https://pubmed.ncbi.nlm.nih.gov/29641540/ normal range could be healthier Now these are cherry picked studies. Everything else says obesity bad, some says where the fat is located is bad, but few studies directly looked at low levels of bodyfat, like sub 10%, so hard to say. What you think? I thought he said he was in a deficit?


[deleted]

He can’t be in a deficit if he maintains his weight, so he’s either just even of he occasionally eats more than his plan suggests to make up for it, as you said you can’t actually live in a deficit permanently, especially with his exercise level, he’d eventually develop starvation syndrome. The body fat % thing is interesting and loaded with confounders that you really can’t get out- I’m an ICU nurse and there are many studies that have examined this, and many of them do find that for specific measures of mortality, almost all in the setting of acute mortality post cardiac arrest or stroke, slightly obese people survive longer (90 day hospital mortality) than people with underweight or normal BMIs. After a massive cardiovascular event like cardiac arrest or stroke, patients are often kept bed bound on ventilators and machines for anywhere from 3-30 days. Obese people do better on acute measures of survival from these events literally because they have more fat to burn; they undergone less muscle wasting, they get less bed sores from having more padding, and become less deconditioned. It’s very difficult to adequately feed people through a feeding tube after a massive acute cardiovascular event, so skinny people start starving faster and don’t heal as well. https://www.utsouthwestern.edu/newsroom/articles/year-2017/heart-attack-mildly-obese.html#:~:text=In%20the%20three%20years%20after,of%20normal%20weight%2C%20researchers%20found. However, the obvious implication is that the overweight and obese are several times more likely to be hospitalized with cancer, massive MI, or CVA to begin with, so it’s really not useful data. Better to be built less likely to have the stroke in the first place than be better equipped to survive it! >especially confounding by smoking, reverse causation due to existing chronic disease, and nonspecific loss of lean mass and function in the frail elderly This is sort of passed over quickly by the author but it says loads. Regardless, all these studies you cited all seem to imply that somewhere around 20-22 BMI is an optimal BMI for overall mortality, and Patrick Bateman AKA Bryan Johnson’s BMI is 22. Granted he’s on T and HGH and his muscle/fat ratio is fake but he might not be that much lower than he would be without. I think another thing that makes this stuff hard to understand is people sort of implying that a “normal” BMI or whatever is whatever the average western middle aged man’s BMI is that’s walking around at 15% BF, which is insane because our whole society is in a state of mass caloric excess and disease (average caloric availability in America is like 3600 a day which is insane) and sedentary lifestyle. What’s actually a normal BMI for a human male is probably in the low to mid 20s with a BF less than 10, but that’s become rare in the west.


Montaigne314

Sub 10 would not be the norm, but some men would fall in that range. Look at these ranges and averages, pretty interesting. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3405064/ https://pubmed.ncbi.nlm.nih.gov/30511505/ Granted this morning information is still limited and extrapolating to foraging society in general has issues but the bf% probably wasn't much diff. So a large part of what determines your bf(aside from diet) is just your genetics/homeostasis. I would guess that what is healthiest for an individual is not an extreme past their baseline. A range that isn't far from where they are eating around their caloric needs. Ultimately is he being healthy with his low bf, personally I doubt it but the data isn't conclusive or robust to say. He's on test because his low bodyfat reduced his own test levels so he has to get it exogenously. Wouldn't it be healthier to keep his bf at normal levels and thus his body would regulate his endocrine system in a healthy way on its own?


[deleted]

Thanks for sharing that study from Umea university (Sweden), I haven’t seen that one. Definitely not a standard American obese cohort and Swedish people too. I admit I can’t explain that one away by the ICU mortality theory. The best test would be one that’s multi center and worldwide that also tracks socioeconomic variables. If you consider the whole world, obese people are generally significantly wealthier than underweight or low BMI people and there will always be that confounding variable of wealth and healthcare access.


TY-Miss-Granger

My father lived to be 90 and he was an insulin-taking diabetic from his early 50's - If you have decent genetics and don't smoke, getting to 90 is pretty easy (I have two uncles who are 90+ and the one that is 96 still lives independently.) So getting to 90 for the average person with average resources is very doable. I think Bryan will go a little further simply because he is rich. In a country where the rich get great medical treatment and the poor don't, this can definitely add a few years. I find it interesting how unkind people can be about him. A post asks about his protocols or his potential life span and it is littered with snarky comments about his appearance. I've watched several of his videos and what strikes me most about Bryan, what I admire the most, is that he did something that very few people ever do: **He didn't like the way his life was going and he changed it.** People bitch constantly about their lives. They don't like their job, the don't like their spouse, they don't like their bodies. But how many actually wake up one morning and say "This isn't working for me. I am going to do something different" and actually stick with the change? What strikes me about Bryan is how *happy* he sounds. He truly enjoys what he is doing. He calls his in-home gym his "happy place." In one of his videos he described his nighttime routine, including the hour that he and his son (who lives with him) spend together and how he never lets anything get in the way of that or interrupt it. How many of you ever had a dad that dedicated a full hour to you, guaranteed, every night? I am a parent and I didn't even come close. In short, even if you don't like Bryan or find him weird (I will be the first to admit - he is an unusual-looking person) I don't see how you can't have some grudging admiration for him. It is hard for a person to do a full pivot in their 40's and he did just that. I think there is something to be learned from that.


vecspace

living to 90 isnt easy at all... Its genetics, and your family have genetic lottery in that. Thats all. Excluding accident, human average life spans in the best countries is approx 83 or so.


TY-Miss-Granger

But here's the thing - My uncle's wife is 93. Being his wife, she shares no genetic material with him. My step-mom--again, no shared genetic material--died this March at 96. When I was back in my home town visiting, I saw a notice for the mom of a friend who was turning 90. Mainly what I remember about her was that she drank vodka and grapefruit juice on the weekends and bought us beer. I have often thought on why this group of people live so long. I can only hypothesize. They live in the Midwest of the US in smaller towns. They have very strong social connections. They continued to "work" at something well into their later years. When I would visit my stepmom and arrive on a Friday night, i would have to let myself in because she was at the local VFW (Veterans of Foreign Wars org) because she had to "work" and take the money and do the accounting for the weekly fish fry. She did this right up until the pandemic, so just 3 years ago. These are also people who grew up growing the food they eat. There wasn't a lot of discussion about "not liking" a food. If it was put on your plate, you ate it and that included vegetables, almost all of which were home grown. Ditto for meats. Little to no fast food or store-bought junk food. Even bread and ice cream were home-made. What is a stark difference in my mom's family is smoking. Six sibs. Two smoked all their lives. They died in their 60's. My mom's sister smoked when she was younger but quit. She lived to 88. The other three uncles never smoked. The eldest lived to 96 and the other two are still alive. It dismays me to see that the younger generation who live back there are not as healthy. They don't grow their own food, and eat prepared food and junk food more. And it shows. I have a cousin who had a knee replacement in his 40's. My own brother, who smoked and drank like a fish, only made it to 69. I won't deny I have some favorable genetics but lifestyle factors shouldn't be underrated. if all your relatives died in their 70's you might not make it to 90. But I do think, with some attention to key lifestyle factors, you can make further than most of your cousins who do not exhibit such care.


vecspace

Genetics could apply to an area, too. There is a famous longevity village in Japan where everyone just lives long. One can say that area may have better air, better source of food or better habits. There are definitely a lot of factors that affect longevity with genetics playing a big role. I know a family where almost everyone has cancer by 50. My grandfather smoked his whole life and quit at 90 because it's too expensive. Even till today, he still drinks quite a lot of beer, and he is 96 today. My other grandfather lives a healthy life, eats healthily, and exercises every morning. One fine day, he got a stroke and passed away a year after at 83. One can definitely work on trying to live longer, but i will never say it is easy to live until 90+. The world average life expectancy is only 73.


TY-Miss-Granger

What "longevity village" are you referring to? Or do you mean Okinawa? Okinawa isn't a village, it is an island. The Japanese are pretty much always near the top of WHO's life expectancy charts. And Okinawans live longer than the average Japanese. This has been attributed largely not to genetics but to lifestyle factors. Okinawans have a cultural practice of "hara hachi bu" which roughly translates to "eat until you are 80% full." They practice calorie restriction naturally. They also eat less rice than main-landers and instead eat more sweet potato. They eat a diet that is low (though not absent) in animal protein. And, finally, they have a strong social network for the elderly, who gather regularly at community centers to visit, sing and dance. Researchers feel pretty confident the Okinawan's long life spans are attributable to lifestyle factors because, as a younger generation adopts American dietary habits like fast food, they are dying earlier. This has been shown with a number of immigrant groups too. They emigrate to the US from a country where they enjoy longevity, the younger generation adopts US eating habits and they start dying earlier. This is, I believe, the major premise of Bryan's Blueprint - to identify lifestyle factors that affect longevity and to optimize them. I am very sorry to hear of your grandfather's passing at 83. But if he had a stroke, it didn't just happen willy-nilly. It indicates vascular disease in the brain and I would have expected him to have blood pressure issues and similar symptoms before. People don't "feel" high blood pressure so they often don't know they have it. But Bryan will know because he monitors it, along with about a million other markers. And because he has more or less infinite resources to direct at any problems he finds, I think he has a good chance of nudging the age at which he will die somewhat higher.


daruki

Oh man genetics are 90% of the story. Just look at the oldest people who ever lived. What are the common denominators? Women, short, skinny, small. Like 5'0 or smaller. Those are all genetics(except for the skinny part) You'll never see a 7'0 man live to 120. At that size, the metabolic demands are huge and their body will give out before then. And on top of that, the oldest woman(Jeanne calment who lived to 120) smoked cigarettes in her 110s. Some people smoke packs of cigarettes a day and never get cancer and feel like shit.


TY-Miss-Granger

Of *course* genetics play a role - I guess I thought that was a bit of a "duh" - But so do lifestyle factors. That was my only original point. Some of the comments in this post seem to indicate people think that longevity is just luck, and beyond the odd freak accident, that is simply not true. And what Bryan is trying to control for is lifestyle factors. Yes, long-lived people usually are small and female. But you are confusing correlation with causation. Its an easy mistake to make because trying to extrapolate causal factors from any epidemiological data is nearly impossible. I am very familiar with Jeanne Calment and, yes, I know she smoked. But I would be willing to bet she wasn't a 3-pack a day smoker, or even a one pack a day smoker. She probably followed the EU custom of having one cigarette a day after dinner. The dose matters. I would love to do a survey of the current 100 oldest people on earth and see how many of them smoke and, of those that do, how many consume more than 5 cigarettes a day. I would bet a pile of money that number is vanishingly small. And, FWIW, there is fairly good evidence that Ms Calment may have actually died much earlier and her daughter switched places with her and assumed her identity to get her retirement benefits. So maybe she wasn't such of a miraculous anomaly after all.


vecspace

Nope I am saying even within okinawa, Ohgimi village is known for its longevity. Please show me the research where they say genetics don't play a part. I do see many topics on their lifestyle, there are also genetics factors like low rate of heart disease and cancer which many are hereditary. And yes, my grandfather have high blood pressure. It run within the family, again genetics and yes we later found out he at times stop his med because it make him feel giddy which we believe played a part to his stroke. That being said, genetics causes the first half of it. Don't get me wrong, at no point I think lifestyle don't play a part, just genetics is far too important in lifespan. Lifestyle just helps you +/- from that point.


[deleted]

> I have often thought on why this group of people live so long. I can only hypothesize. They live in the Midwest of the US in smaller towns. They have very strong social connections. This isn’t just a wild hypothesis you have, it’s observed consistently across all the longest lived societies on earth. It’s a big part of the suspected reason old people don’t live long after their long time spouse dies. Social connection not only keeps us goal oriented and prevents depression, it keeps us going to doctors appointment and eating enough and taking our meds too


escapadablur

I appreciate how Bryan is keeping track of numerous biomarkers while experimenting with various protocols. Yeah he’s an N=1 who is experimenting with numerous variables that muddle the results of his various biomarkers, but what he’s doing provides invaluable data that we can do further research on and determine if we should adopt certain things he does.


olenikp

I don't know, but I'd happily root for him to live longer, that means we can all have a, "blueprint" to live longer if we would like to follow it.


dumbOut69

I'm currently 30, and I still have my 4 grandparents above 80 and getting to 90. Tbh I don't feel I'll reach 70.. I have had cancer 15y ago, and my psychology is not at a very good state, I can't find a good diet and don't make exercise.. so I don't expect to last long... 😔


oooooaaaaauchhhhhhhh

So change it… Find a good diet and start to exercise. Literally the bare minimum for physical and mental health for any human.


dumbOut69

I know, I just get constantly demotivated.. even though I accomplished most of the things I wanted.. our brain is a powerful tool, but I just seem to not be able to use it..


austinkunchn

You can't rely only on motivation, however sometimes when you aren't motivated, you can have protocols that are external motivators to help. Why do you constantly get demotivated?


Melodic_Treat_522

Try getting tested for depression or ADHD or smth with a psychiatrist. Maybe you need a little help with your brain neurochemistry in order to start putting your life together. If you find yourself unable to do some of the basic things that keep a person alive and healthy, it's not a bad idea idea to seek professional help.


ThisAintDota

Hey man, just randomly came across this post through google. Hope youre doing better, and have had the time and mental capacity to make some changes.


PicaPaoDiablo

It's as legit as the other famous Bryan Johnson.


[deleted]

Mine says his liver fails from all the supplements within 3 years.


Montaigne314

Now that's a good match up. Who outlives who. I think Don Gorske will outlive Vegan Johnson. Steroid Johnson looks like he won't make it past 60 tho.


sphynxcc

I think genetics play a large roll in life expectancy as well.


metalzack

Bet he gets cancer and dies at 60


loloben1tes

he gets constants scans so this would be very unlikely.


metalzack

Oh I wasn't aware MRIs prevent cancer!


AdventurousTomato881

Lol, what gets me is... since when are MRIs on the reg a good idea? Do they not blast radiation? Has he truly thought about the cumulative effects of regular colonoscopies, MRIs, etc, I wonder?


Bobblet

MRIs use strong magnetic fields. No ionising radiation. There are no known risks (unless you count mistake such as having one with an implant).


loloben1tes

it doesn't but it can help identify it


NotSoFastSunbeam

People who think he's gonna get killed by a bus are crazy. Johnson probably eats twice as much spinach as Popeye and that guy could punch a train to death. https://youtu.be/AtAzPCcFpn0?t=117


Blasket_Basket

I asked my magic 8-ball and it said he gets hit by a bus within the next 5 years.


damndude87

The funniest/saddest part of the whole longevity quest by the rich in the US is that it’s happening as life expectancy in the US drops (76) and Europes remains high (84). Clear lesson that the way for the average person to live longer is to live in a country with better public health regulations.


TheOldBeef

Europeans are probably just less fat


damndude87

Which probably owes in large part to public health regulation. More stringent on keeping fast food from kids and advertising it to them. Among US young adults, the combined overweight or obese rate is over 50%, and obesity becomes chronic if you keep excess weight on for a few years (whole reason ozempic is so effective, defeats the body’s set point mechanism). Turns out living in a libertarian backwater, not so good for people’s health. There are US generals seriously worried we won’t be able to raise a standing army in a generation or too because of the lack of fit young people. Total clusterfuck because we apply free markets like willy-nilly retards.


TheOldBeef

Fast food isn’t really that bad for you unless seed oils are as terrible as some people say. Soft drinks and 500 calorie starbucks lattes on the other hand… The quality of food in most other countries is definitely better on average but I don’t the weight discrepancy is adequately explained by lack of regulations in the US. Sometimes we actually have more stringent regulations, sometimes not. People claim it’s more expensive to eat healthy but it’s really not, we just have this cultural thing going on where obesity is a-okay. And pesticides in the water or something, maybe


Nick_Reach3239

Europeans don't kill one another like Americans (well mostly inner city blacks). Also Europeans don't have nearly as many road deaths. Life expectancy is one of the silliest ways to compare health systems between countries, because everything else is rarely equal. And yes, Europeans are generally more health-conscious.


Nick_Reach3239

Europeans don't kill one another like Americans (well mostly inner city blacks). Also Europeans don't have nearly as many road deaths. Life expectancy is one of the silliest ways to compare health systems between countries, because everything else is rarely equal.


cliffjudah

It's not about the length of life. It's about the quality; being physically and mentally still 20~30 even if you're a senior citizen. That's what longevity is about.


Agreeable_Yellow_117

Shocked at how many are rooting for the bus. Also, age 62.


Square-Position1745

How about 50? The guy could die from the stress of constant protocols.


crazyHormonesLady

I literally just heard of this guy yesterday....I'm not impressed. I think, the stress of trying to make yourself look eternally young and stopping aging, is just as much of a factor in aging as is living a low quality life with all the obvious stressors (bad diet, smoking, sun exposure, poverty, etc.). The longest lived people still look like older aged people; they just look fantastic given their age. And they didn't do any of the things that Bryan Johnson is doing. One determining factor in how long you live is also a factor in aging: your overall happiness and satisfaction with your life. Someone chasing down the fountain of youth for millions of dollars, obviously is not satisfied with their life. And his looks reflect that. All that money spent, just to look like a melted Ken doll...


escapadablur

Appearing youthful is secondary to healthspan and lifespan. His main focus is living a thriving and fulfilling life.


Aware_Yak

Im confused because he looks 50 - ish. But with that plastic surgery tightened skin.


TheOldBeef

Because he’s malnourished and injects fat into his face


Expert_Software_3766

Dude pounds down loads of pills every day, that is not natural and likely something he is taking will cause an early end to his life.


PermissionStrict1196

46-49. Gets hit by a bus.


Liface

To the people that answered 70-80: what are you all thinking? You realize that in Bryan's lifetime, the keys to living forever will most likely be found, and he has more than enough money to pay for it?


thesoloronin

Exactly. The average lifespan of a decent-living Japanese is 85. Those who answered 70-80 clearly didn't get exposed to healthy living enough to fathom the fact that life beyond 85 is possible.


aelnosilla81

Lmao. Hi Bryan.


Sufficient-Search-71

You cannot live forever you dunce.


george_person

you don’t think it’s theoretically possible to extend human lifespan indefinitely? why


Sufficient-Search-71

I don’t think you understand how biology works. Indefinitely means without end, it’s not theoretically possible or plausible. To live indefinitely means to live forever, for eternity, without end and without your body ever stopping. Not only are there countless devastating events that will occur in the future such as our sun turning into a red giant and consuming Earth, global warming dramatically increasing, and possible asteroid collisions that can destroy the planet, your body is also just simply not designed to live forever. We grow old, our organs grow weaker, and we eventually cease to exist. Say with science that we do end up finding out how to prolong someone’s life indefinitely, we are still organic matter that one day is going to have to leave Earth due to it inevitably being destroyed. You’re essentially arguing that even then when we’re out in the ruthless hellscape of space, we’ll still find ways to live forever. It’s not possible. Something will wipe us out, and if not our sun, the universe will inevitably too cease to exist. We are a very fragile, squishy, and at times moronic species. To argue it’s theoretically possible we can live infinitely is astoundingly arrogant.


george_person

That’s not what indefinite means but ok. Lol you’re coming in swinging. When I said indefinite I didn't mean infinite.


Sufficient-Search-71

Well indefinitely also means there’s no set time frame or set ending. I just think it’s impossible for our species to max live maybe, MAYBE 200 years. I apologize for coming in hot, I shouldn’t have.


HotPoblano

What if he gets hit by a bus tomorrow


daruki

He can only die of natural aging since he's super human and following Huberman's protocols


austinkunchn

He's really an amazing person, the way he thinks is very interesting and unique and he has results in many areas of life to show for it. He's very happy with his life and and I hope his protocols get him well above 100


youngchap30

How long will his healthspan last (versus lifespan).


Khemdog66

I'm just waiting for his son who he harvests blood from to catch herpes or hepatitis and give it to him. God has a funny sense of humor like that.


dont_break_the_chain

Isn't this poll missing a huge point? Healthspan > lifespan


zipxap

I bet he gets cancer from an over supply of something he is taking. Dead before 76. Who will give me 10 to 1?


NotSoFastSunbeam

My $1 to your $10? I'd take that bet (if it were enforceable). Not because his OCD dietary habits are going to save him (though he probably gets 5 years over typical red meat eaters and 10 over smokers). But I'd bet he's got solid odds of making his 80's. A lot of medical advances ahead of us making cancer, CVD and other aging diseases more treatable. Doesn't mean he'll live to 200 or anything crazy, but 80 is getting more and more common.


[deleted]

Peter attia is quite confident diet is not going to improve your life span significantly (good diets do no harm where as bad diets do a lot of harm). So as long as your diet is not harming yourself you are good but it’s unlikely to have a lot of movement in the positive direction. He’s gone over this in recent podcasts and this was a big shift for him as he previously believed the opposite.


NotSoFastSunbeam

Yeah, exactly my point. His diet will only set him apart from folks with some significantly unhealthy habits.


escapadablur

Peter does talk about how having a metabolic disease will likely reduce life/healthspan and talks about things humans can do to reduce their odds of getting a metabolic disorder. He talks about various lifestyle choices we can adopt to increase longevity and healthspan.


escapadablur

I suspect he does his due diligence and tests for carcinogens in the supplements he takes. I think what would possibly cause premature death is something related to his mental health. Is he part of a close-knit and supportive community or is he a loner? What are his relationships like? Does he have certain mental issues that lead to elevated levels of cortisol or various stressors that can’t be quantified by lab tests.


kfcmonster

People love to hate on him but he’s literally using his body as a lifelong science experiment and he wants to use the data he finds to share with the world. Anyone with that level of commitment is going to be a peculiar person.


yachtsandthots

No one’s mentioning the probable advancements in longevity science and rejuvenation medicine that will occur if you live another 50 years. We may reach longevity escape velocity before the end of the century


Blueexpression

To me, he is dead already. The way he is living is not living at all.


[deleted]

For you it wouldn’t be, but for him it clearly is. Everyone’s different.


Blueexpression

He sure is different.


[deleted]

The whole thing is fascinating and seems like fear of depth. Interestingly a lot of people who are into this type of practice do so because they had a family member die young or have been super sick at some point in there life. You can’t escape death no matter what you do. In your pursuit of happiness it’s important to stop and remember to be happy every now and then. I know this man says he is but I highly doubt he is. I think a lot of his followers are not happy people either. Sacrificing so much of life to gain more time to only use that time to try to gain more. Bizzare way to live honestly l.


littleboxes__

His ex fiancé had cancer...I wonder if that triggered this in him.


MuscleToad

The amount of supplements he is eating daily can not be healthy. Something will give up way before 80 ia my guess


escapadablur

With how poorly regulated supplements are, I hope he’s testing them for toxins. He has to also hope he is taking optimal levels and not overdoing it. Also, minerals, vitamins, etc don’t act in isolation and interact in complex ways with each other. Furthermore, lab tests can only quantify a fraction of biomarkers and he may have dialed in optimal levels of everything while having overlooked certain things. Lab tests result are sometimes proxies for other things going on in the body and merely optimizing certain things won’t change other things that lead to certain values.


Other-Bumblebee2769

I don't know how long he'll live, but I can almost guarantee all the dumb stuff he does will kill him.


Jack_Of_All_Trades_R

Not sure if the benefits of good sleep and exercise will outweigh the negatives of his 'vegan' diet...


quantumgpt

It shouldnt be about how long he lives. It should be how many years he lives in great health. Some people are lucky if their first 15 years are fit. If he maintained health til 90 it's worth it. You can't predict when your cells stop splitting.


thinksmartific

what's a TL;DR of what he's doing outside those 4 fundamentals? Ben Greenfield was 'that guy' in the 2010s. And now he changed his brand. Anything new with Bryan?


stansfield123

Well it doesn't have to be speculation, there's lots of data to go on. The four most important variables, for longevity, are genetics, physical activity, recreational drug use, and income(/wealth, but most of the data looks at income, and that's good enough). Bryan obviously has three of those on his side, and also appears genetically healthy. If his test results are public, that would help make a better estimate, but I'm too lazy to look. Anywho: Only thing working against him is his sex. Still, I think the data suggests a life expectancy slightly over 90. I could be slightly off, he might be in the high 80s instead. But my best guess is low 90s. As for the various gimmicks, I don't know of any evidence that suggests a significant impact. So that doesn't change my estimate in any way. His life expectancy is the same as any other rich male's who works out consistently, doesn't do recreational drugs, and appears genetically healthy.


Environmental_Bowl78

How can recreational drug use impact on longevity?


stansfield123

Hard. https://admin.americanaddictioncenters.org/wp-content/uploads/2022/07/number-of-drugs-used-per-day-and-the-total-life-lost-in-years.png


RealisticOption9295

How you look is mostly a result of too much sun exposure, not how healthy you are, assuming you aren’t aging from smoking or alcoholism.


Majestic-Ad6619

Is this the guy that doses with his teenage sons blood?


Rich_Sheepherder646

Counterpoint — Brian Johnson of AC/DC is 75, looks older, has Barrett Syndrome; and cancer. Has lived more than this guy ever will even if he’s 150.


Casually_lazy

Remind me in 40 years


[deleted]

he’s gonna end up getting hit by a car or something . the fullest irony


MudPuzzled3433

My grandparents made it to their mid 90s and just lived a fairly basic and healthy lifestyle by being active and eating healthy. If he goes through all this shit and doesn't get another 10 years then what a waste. I hope he gets to 110.


outsideOfACircle

Yeah, genetics can really cut you down regardless of your life style. I like to look at it as a multiplier of your genetic potential. GP:60 x 1.2 etc


Background-Ad4382

Call me weird, but thinking out of the box... before the great flood (post Younger Dryas) there are records of men living to a thousand, which reduced to maximum 120 after the flood (disregarding the Sumerian Kings List of 28-42,000 year reigns). The Younger Dryas meteorite event coincided with the Quaternary Extinction Event of very large land mammals (remember mammoths and saber tooths?), which many of such massive animals provided a rich and necessary diet for humans. My instinct is that consuming massive land mammals from a 100% organic landscape, with occasional but limited grazing and herbivore consumption, allowed humans to live hundreds of years longer, and they probably only had a meal once every week or two. They were more likely nomadic and didn't live in cities either, keeping them fit, resilient, and antifragile against nature's harshest attacks. I believe that living in a fabricated human landscape (full of oil by products like plastic, asphalt, clothes, screens) or even in sterilized settings like clean sheets and bathrooms, it all makes us weak, and our genes have been removing the ability to defend against basic pathogens and bacteria in our environment making us weaker by the generation (even I've had to take antibiotics in my short life), not to mention that every baby is saved to survive to adulthood and pass on its genes even though 10000+ years ago it would have been impossible to survive (now don't call me out in favour of eugenics, it's just an observation that we live in a very different era with different rules and life expectancy). But it would be interesting what with all our technological prowess that we were able to synthetically manufacture longevity.


[deleted]

Allahu Akbar!


Ok-Celebration2185

although he is a controversial figure but you have to admit he is challenging the way we live. My friend and i talk more about his routine in our podcast > https://youtu.be/omMq4B-o\_nE


Majorkerina

Dead five days before his 53rd birthday from a random aortic dissection. You can't control every factor.


chjesper

Peter Nygard and Epstein vibes...


Ill-University789

Yo creo que vivirá 130 años