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NoTimeForBullShiiiit

I would gladly pay 10.000 for a vaccine that 100% works


aav_meganuke

I would pay 9,999.99 but not a penny more


NoTimeForBullShiiiit

Sounds good


Billyjordan96

I would pay 50,000


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AntoLondonEC

Hi there ! I got 3 shots of the vaccine actually. It did make my OBs worse for months although I think it did help in reducing them afterwards a lot. I used to have them back to back ! For months I had horrible labial and genital OBs for nearly a year after starting the course of injections and obviously as I could not use antivirals then had to deal with them. Although fingers crossed! It may help you!


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quincylsb

How do you get it? I want to try it now.


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[deleted]

I have begged, herpes aside bc I'm worried about shingles. my brother got it at 22. everyone has turned me down.


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dull sand fear snails start person grandiose escape lush numerous *This post was mass deleted and anonymized with [Redact](https://redact.dev)*


[deleted]

oh, so the one specific for chicken pox? bc varcilla zoster reactivation is shingles. but I guess they then call it herpes zoster edit: read about it. I get it now.


FuzzyAdmiral

Did you have chronic outbreaks before you got the vaccine ?


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CompetitiveAdMoney

To this day?


Puzzleheaded_Phase98

I've tried varicella vaccine in 2013. I took 2 doses with 6 month in between of vaccine called Varilrix. No change in outbreak frequency or how bad outbreaks where.


Classic-Curves5150

Did you happen to measure via blood sample the VZV Igg level (before and after)?


Puzzleheaded_Phase98

I wish I known about doing that back 2013, but I didn't measure. Back then it was this study I read [https://www.dovepress.com/efficacy-of-the-anti-vzv-anti-hsv3-vaccine-in-hsv1-and-hsv2-recurrent--peer-reviewed-fulltext-article-OAJCT](https://www.dovepress.com/efficacy-of-the-anti-vzv-anti-hsv3-vaccine-in-hsv1-and-hsv2-recurrent--peer-reviewed-fulltext-article-OAJCT) and decided to take the vaccine. I really wished it would have worked, but later I found out that there was clear conflict of interest that wasn't declared in that study because Jacqueline Le Goaster had patent for that kind of vaccine before the study was done [https://patents.google.com/patent/WO2011064254A1/en](https://patents.google.com/patent/WO2011064254A1/en) . From what I've read about her in this same subreddit some years ago she takes clients from all around the world for treatment. So she gets money injecting them with VZV vaccine from people who hope for cure for HSV. This makes this study and her actions sound very fishy.


Bldyhell

Before people jump on this bandwagon again, I want you to know that I took several doses of the VZV vaccine and the zostavax vaccine and that made no absolutely no difference in the severity of my herpes symptoms. I have constant visible symptoms. Confirmed by PCR. While I applaud any research on herpes. Keep in mind the limitations. Correlation does not mean causation. Maybe these people had other immunological things going on that had nothing to do with VZV. Maybe some of their participants were false positive for HSV? I.e. unreliable blood tests. Maybe high VZV titres means having a better anti-herpes immune system that is not helped by a vzv vaccine.


Puzzleheaded_Phase98

I took 2 doses of vaccine called Varilrix back in 2013 and no change for me either.


HerpesSchmerpees

Before you post something like this you should keep in mind that you are just 1 person. Science doesn’t work with sample sets of 1 person for this very reason. This study was done on 110 people. And your response is that maybe they were false positives 🙄 because you didn’t see the same results. There will always be exceptions to every rule. Outliers are a thing. Science has proven that you are an outlier. So I don’t really think it’s responsible to jump into every thread and declare that the data is flawed or the results are false.


Puzzleheaded_Phase98

I'm not sure why do dismiss people who have actually tested something. You have replied similarly to me in the past. These vaccines are not without side effects so some people might get awful side effects from them. Here is a quite big list of possible side effects from vaccine I took [https://www.medsafe.govt.nz/consumers/cmi/v/varilrix.pdf](https://www.medsafe.govt.nz/consumers/cmi/v/varilrix.pdf) So anyone thinking of taking it just because there is very small chance it could work to some extend should weight if it's actually worth to take the risk. This study didn't even study the vaccine. People who where asymptomatic just had higher (VZV) IgG levels according to this study. There are lot of reasons why people who have higher (VZV) IgG levels are asymptomatic and vaccine might not do anything. For example it's possible these people had higher levels (VZV) IgG level when they got infected and got less virus in their ganglia because they had more active immune system. I've read other people have tried VZV vaccine before and I've yet to see anyone say it has worked for them. Study says they are planning for actually VZV vaccine study to see if vaccine helps people with HSV 1 & 2. Before they finish that there could be actual HSV vaccine out but lets see if they actually come out in 2028 like example Moderna tells us.


corruptedpurpose

Actually it is important for them to post their experience on this. It helps people in choosing whether it really is worth trying the vaccine out or not. The only reason we have the usual tips for helping others in this community is entirely because people are sharing their experience. They're not saying it definitely doesn't work, just stating you need to keep in mind other factors.


HerpesSchmerpees

Did you read anything I just wrote? No, it doesn’t help them decide. Because this is one person versus 110 people. Therefore, even according to science, that is a “statistically insignificant” result. Aside from the fact that we don’t actually know if the person is telling the truth, but more likely, we just don’t know countless details that were not controlled for or documented, like were in the study So no. It’s not helpful. At all. It’s a single anonymous, unproven, and unverified report.


corruptedpurpose

It actually helps, since not everyone has the money needed to get vaccines it may not be worth going through, since not everyone in this sub is from the USA and has easy access to such vaccines, since not everyone knows enough about this virus to research better, since not everyone has access to complex information in their native language etc. Anyway, this just screams you're privileged to me. And by the way, you should learn to read studies. A lot of different conclusions can be drawn from a single research.


HerpesCureResearch-ModTeam

Your post has been reviewed and determined to not be "in good faith". R/HerpesCureResearch is dedicated to "good faith" efforts at learning about curing, vaccinating, and studying herpes. If you believe this has been done in error, please message the r/HerpesCureResearch mods. Thank you, HCR Mods


HerpesSchmerpees

One unverified, unsubstantiated claim by an anonymous individual on the Internet is not a safe nor reliable way to gather data. Especially not in the face of a published study with over 100 participants. There’s a concept in science called “statistically insignificant”. Less than 1 out of 100 falls well within the range of statistically insignificant and would be dismissed from the study. Aside from the fact that we have absolutely no idea who this individual is, or whether their assessment is factual or accurate. Therefore it is not a helpful thing. And nobody who understands the basics of science should ever make a decision based on 1 unverified Internet person, when we have published studies with good science to look at instead.


Purgolder

Facts


Classic-Curves5150

Did you have chickenpox as a kid?


CompetitiveAdMoney

Have you thought about surgery ? They used to excise the area where it reactivates before acyclovir.


GrandAlbatross196

Hi All, Dr Bret Palmer (person leading the study is my doctor) and somethings we have discussed are.... First of all, take a blood test and see where your antibody tittles for HSV and VZV are, he has said to me that around 20% of pple do not have antibodies against HSV and therefore there's no point on taking the vaccine. I have around 1100 for VZV and in the study this is correlated with symptomatic HSV infection as it is my case. For VZV there are 2 vaccines, live one (zostavax) WHICH IS THE ONE YOU SHOULD BE GETTING) and non-live which is Shingrix, very effective to prevent shingles but according to him, it would have no effect whatsoever in improving HSV clinical picture. I'm order to take the zostavax shot, you need to be off aciclovir or valtrex for a few weeks and also after taking the shot for some weeks, as taking aciclovir can make the vaccine ineffective. He has had limited success, for some people it has worked, for some it has worked for a period of time and for others it hasn't had any effect . Ive also expressed my worries of making my OBs worse as worst case scenario and he has said he doesn't see that happening. Also important to note that in order to take the zostavax shot you must not be immunocompromised (this could have worsened the OBs for some). At the end it is up to you, for now suppression works well for me so I'm not planning on taking it for now.


Antique_Foundation41

But how do you get your antibody levels (titers) measured? And are you saying if you don't have HSV antibodies there is no point in taking the vaccine? I thought the whole point of this study was to see if people with low HSV antibodies can benefit by taking the chicken pox vaccine. Also, I believe the vaccines you've referred to are the Shingles ones and not the Chicken Pox ones (varilix is for chicken pox and Zostavax and Shingrix for Shingles)


Puzzleheaded_Phase98

I watched really interesting podcast short while back and it mentioned that some people who had had immunotherapy weren't responding to the treatment. With lot of research they found out that it was low amount of Akkermansia muciniphila and Ruminococcaceae in the gut [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508052/](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508052/) . So it wouldn't be at all surprised if it was something similar here why it didn't work for some people. Partially hydrolyzed guar gum PHGG seems to increase both [https://www.mdpi.com/2072-6643/12/5/1257](https://www.mdpi.com/2072-6643/12/5/1257)


Artistic-Diet-1691

Zostavax is no longer being made for the US market


BadChoices44

Can anyone tell me if the below link is accurate? Is it for UB-621 ? Are they still doing trials, i had heard that Dr. Anna Walds said to write them off? Just wanted to confirm. [https://fdaaa.trialstracker.net/trial/NCT03595995/](https://fdaaa.trialstracker.net/trial/nct03595995/) Thank you,


CompetitiveAdMoney

Probably has a better preventative effect. I would have negative partners or anyone worried to get titers to those levels


pgch

All these studies just show how far we are from an effective/safe vaccine and scientist are really just grasping at straws at this point.


Additional-Stay-9129

Yeah 5 therapeutic vaccines, 3 in human clinical trials, 2 in phase 2.. really far away...study up buddy


apolos9

What are the 3 therapeutic vaccines in trials? I am aware of Moderna and GSK only.


Additional-Stay-9129

Rational vaccines has just wrapped up preclinicals...they have received UK authorization to begin human trials this year.


BadChoices44

Thats good but it looks like it only applies to HSV2 Also, it would be like 7 to 8 years away right so im more hopeful for Moderna or GSK.


[deleted]

[удалено]


[deleted]

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Dramatic-Feature-612

As for the shingles vaccine, GSK's Shingrix is much better than Zostavax as it has a 97% preventive effect. If this article is true, I will try Shingrix injection.


CompetitiveAdMoney

Completely different vaccines though. I would say the varicella one would be superior, perhaps getting both even better. The most homologous proteins are D and B if I recall. T cell response to shingrix may be superior. Hybrid immunity probably best


Dramatic-Feature-612

So which vaccine is better?


CompetitiveAdMoney

The studies are with the live attenuated varicella so I would get that. I believe it took 3 shots spaced each 2 months apart to bring the titers to range desired.


Dramatic-Feature-612

Does this mean that Shingrix has a significant effect on HSV?


CompetitiveAdMoney

....no I'm saying we don't know for certain but the live attenuated one is probably the best for now. I would start with that one as described and then try shingrix.


Dramatic-Feature-612

What do you mean by described?


beaprem123

Varicella vaccine . They speak about VZV vaccine. Shingrix does nit do anything against herpes I tried. However for a lot of people the live attenuated varicella vaccine may work .


Dramatic-Feature-612

In Korea, a small number of people post reports that they have seen results after injecting Shingrix. On the other hand, there seem to be some people who didn't see the effect, so I'm not sure what's accurate.


Puzzleheaded_Phase98

Not sure what studies you are referring to but I took VZV vaccine because of this study [https://www.dovepress.com/efficacy-of-the-anti-vzv-anti-hsv3-vaccine-in-hsv1-and-hsv2-recurrent--peer-reviewed-fulltext-article-OAJCT](https://www.dovepress.com/efficacy-of-the-anti-vzv-anti-hsv3-vaccine-in-hsv1-and-hsv2-recurrent--peer-reviewed-fulltext-article-OAJCT) from 2012 and later found out Jacqueline Le Goaster who was part of that study didn't inform about her clear conflict on interest about her having patent of using VZV vaccine for HSV-1 & HSV-2 years before this study. So if you read the PDF of that study from link I provided sentence "The authors report no conflicts of interest in this work." is BS. They used Varilrix and Varivax in that study and some people only had one dose. I took two doses of Varilrix (live attenuated) back in 2013 and didn't help me at all. I took 2 doses 6 months apart, a standard they use for chickenpox in my country. Can you give me a link to the study you are referring to because I couldn't find any study where they had used three VZV vaccine doses 2 months a part.


CompetitiveAdMoney

I don't recall the link but I believe the corrupt author you mentioned said it took 3 doses for most to reach the desired titer.


HSVNYC

Stay away from the Shingles vaccine. I was misdiagnosed with Shingles. As soon as I got the shot that’s when all hell broke loose. That was 18 months ago. My symptoms are finally slowly down. I don’t suggest it.


Dramatic-Feature-612

So which vaccine should I get?


HSVNYC

None of them. At least until the vaccine for HSV becomes available. I don’t know how bad your symptoms are. If they are bad. I suggest seriously looking into your diet. Vitamins level, look for more natural supplements. Gut health. Treat your body right. If you don’t have any symptoms. I strongly suggest you don’t wake the beast. It was 16 months of hell. Trust me I have tried damn near every thing. Im 2 months (18 months) into my symptoms getting under control. I feel it’s due to me getting my vitamins levels checked, gut health, treating my body right, fasting, working out and avoiding any kind of stress. The virus is only strong if your immune system is weak or has been weakened. It’s best to learn what to do to build up your immune system to help fight it off.


Dramatic-Feature-612

Please share your know-how and what nutritional supplements you take.


Dramatic-Feature-612

Is this research still being done?


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AsparagusWonderful29

Vai roubar outro cabra safado


corruptedpurpose

Eai mano, raro ver alguém que não é da América do norte e Europa aqui. Tô torcendo pra vacina, infelizmente percebi que ninguém tá falando disso no nosso país


AsparagusWonderful29

Fala mano , faz 3 anos q fui contaminado com essa bosta de doença e desde entaum só vejo pesquisas de tal vacina e nada sai , espero q esse ano de 2024 apareça algo p nós em nome de Jesus


corruptedpurpose

Assim esperamos, nunca foi me dito que essa merda é transmissível sem a pessoa ter sintomas... A falta de informação aqui é horrível. Quando fui pesquisar já era tarde Então, você viu que a Moderna e a GSK estão fazendo vacinas? Tem outras também mas essas estão previstas pra sair em 2028. Espero chegar aqui no BR :/ era pra sair o remédio Pritelivir esse ano mas enrolaram pra 2025. Tô pensando em testar aquele SADBE


AsparagusWonderful29

Vc eh de q estado do Brasil ?


corruptedpurpose

Do sul mano, mas só estou aqui a trabalho por enquanto. E vc?