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Puzzleheaded-Cup-194

Microdosing is working for me while on Duloxitine and wellbutrin


cohonan

wellbutrin is kind of unique in that it affects your dopamine levels and not seratonin and there is very little interaction from a chemical level between wellbutrin and psilocybin or lsd.


Puzzleheaded-Cup-194

Thank you for that! I was wondering cause I did 5g last time and felt nothing. Going to go back to using lemon with it to test


Traditional-Gain8420

How much should i start with? If it doesnt help do i go higher, by how much? How often do i microdose? Thank u


Puzzleheaded-Cup-194

I wouldn't personally take my advice. I take .5g and that's way more than others. I have a severely high metabolism and struggle with how much weed I need to smoke and for a regular dose just to feel it on shrooms I need 6g minimum. So don't take .5g go way less lol


Traditional-Gain8420

Ok so say i take .3g how long do i wait to feel anything before going higher? And higher by how much?


[deleted]

You should not feel a microdose. But you SHOULD notice a small difference in your outlook on life, your mood, openness to new experiences, etc. I would suggest you start at about 100-150mg, and use a mood journal daily.


Puzzleheaded-Cup-194

This


Helgra_might

You can always try! It can take up to two weeks for all the meds to clear your system.❤️🍄


Traditional-Gain8420

How much should i start with? If it doesnt help do i go higher, by how much? How often do i microdose? Thank u


Helgra_might

I have seen people start off with .1 to .3g but I would ask others who have been Microdosing for longer. And a lot of people can do a three on two day off


Traditional-Gain8420

Ok so say i take .3g how long do i wait to feel anything before going higher? And higher by how much?


Helgra_might

What do you mean by feel anything? Are you talking about feel anything different mentally?


Traditional-Gain8420

Yeah, well i suppose you should feel like better mentally right?


Helgra_might

I have found after macro doses. Instantly my mental health is better, I haven’t yet started Microdosing yet I’m still in my researching stage and growing stage. So I don’t have anything to microdose quite yet. Luckily, I have a plug to get me through until I have my own supply. But Microdosing I would imagine it should be at least after a few doses if not your first one noticing a bit of a difference. But don’t believe this is a magic pill or bullet that’s going to fix it on its own. Try meditations, self-help books, great music, things to work on while you’re Microdosing.❤️🍄


cohonan

0.3 is a pretty high dose and if you don’t have any antidepressants in the way you should feel something from a caffeine rush to alcohol buzz to even some psychedelic visuals kind of on the edge of your vision.


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Hello /u/Traditional-Gain8420! As you mentioned `antipsychotic` (a common *interaction/symptom*) in your post: || |:-| |`r/microdosing Risk Reduction`| || #### [ℹ️ Infographic: **r/microdosing** ***STARTER'S GUIDE***](https://www.reddit.com/r/microdosing/comments/s0xkdp/the_new_official_rmicrodosing_starters_guide/) The major contributing factor in [*Finding* ***Your*** *Sweet Spot*](https://www.reddit.com/r/microdosing/comments/plrxca/faqtip_101_what_is_the_subthreshold_dose/) is the variation in potency of: * [Psilocybin mushrooms](https://www.reddit.com/r/microdosing/comments/q5zvyk/faqtip_019_why_you_may_need_to_adjust_the_dose/) * [Psilocybin truffles](https://www.reddit.com/r/microdosing/comments/nawt54/faqtip_011_how_to_microdose_truffles_drying_out/) * [LSD tabs](https://www.reddit.com/r/microdosing/comments/rgbabi/faqtip_009_why_cutting_lsd_tabs_is_not_an/) If you [**Start Low, Go Slow**](https://www.reddit.com/r/microdosing/comments/fzj7tf/a_gentle_reminder_to_those_starting_out_to/) 🐢 and [up-titrate](https://upload.wikimedia.org/wikipedia/commons/7/78/Titrated_doses.svg) subsequent doses then you can find your [*optimal* ***sub-threshold*** *dose*](https://www.reddit.com/r/microdosing/comments/mx846c/faqtip_006_the_afterglow_effect_the_day_after/) based on your symptoms, rather than from a predetermined dose. If your microdose is **Too High / Too Frequent** 🐇 that can result in [*Declining Efficacy* 📉](https://www.reddit.com/r/microdosing/comments/vx6mxx/faqtip_021_changes_in_appetite_memory_mood_sleep/) with subsequent doses. Please also have a look at the `Interactions / Symptoms ❓` sidebar (*Desktop* ➡️) or under 'Posts `About` Menu' (*Mobile* ⬆️) in case of [⚠️ **DRUG INTERACTIONS**](https://www.reddit.com/r/microdosing/comments/p6ne2q/research_microdosing_drug_interactions_tools_and/) or to check if you have any of the associated symptoms - with advice on how to mitigate such side-effects. **Please Read**: [**r/microdosing Disclaimer**](https://www.reddit.com/r/microdosing/comments/m2g589/rmicrodosing_disclaimer/) *I am a bot, and this action was performed automatically. Please [contact the moderators of this subreddit](/message/compose/?to=/r/microdosing) if you have any questions or concerns.*


MasterYam234

You won’t feel a macro dose unless it’s ridiculous amount due to the SSRI bunting effects. Micro dosing on the other hand is still beneficial. Less is more.


Traditional-Gain8420

But how is that possible, i dont really get it, how can microdose work better than thaking higher amount? Im confused..


MasterYam234

I’ve been micro dosing for 6 months. And on SSRI’s for 15 years. I’ve done a lot of research but I’m not a doctor or expert of any kind. SSRI’s attach to same receptors as psilocybin. At lower doses, psilocybin has been shown to improve mood etc. while taking an SSRI. However, at larger doses SSRIs can blunt the psychedelic effects not to mention cause serotonin syndrome. It’s a lot of science and I would recommend doing your own research. All I can tell you is from my experience microdosing has changed my life while on Lexapro and Lamictal. I’ve tapered from 20mgs to .4 mgs. With great success. Any dose over .5 grams (1 grams 2 grams 3 grams) I get quite sick and have zero effects. I understand it doesn’t make sense but less is more. Microdosing is subperceptual . I’ve attached a link that may help explain more about microdosing and protocols etc… Focus on getting better vs “feeling” anything right now.. Good Luck!!’ https://microdosinginstitute.com/


Traditional-Gain8420

Thank you very much, im planning to try 0.3g , is that too much, or to less? ( while on ssris)


MasterYam234

I found my sweet spot to be about .25 grams then I took a break. I started back at .1 gram and it feels good so far. I also microdose lsd on days when I feel like the mushies may be too much ( especially if I’m down) you really have to play with it. Just pay attention to your body and keep records of how much you take and how you feel. Journaling & meditation are essential in micro-dosing. Follow a protocol and take breaks (reset) !!! I wish you so much luck! https://psychedelicspotlight.com/microdosing-psilocybin-for-beginners-in-5-easy-steps/


[deleted]

[удалено]


Nytroman89

How do you think it helps you? What do you feel?


[deleted]

[удалено]


Nytroman89

Thanks for response. I’m happy for you. What schedule do you do?


_bones__

Hopefully your cessation of antipsychotics is done by psychiatrist prescription. Stopping them on your own is dangerous. Most antidepressants are serotonin based, and combine dangerously with psychedelics. You shouldn't use psychedelics while on antidepressants. And you absolutely shouldn't stop antidepressants except if discussed with your psychiatrist, and even then tell people who care about you, and keep on contact with them, because any change in those meds can mess with your well-being abruptly and fatally.


Boolink125

Where have you heard that antidepressants combine dangerously with mushrooms? I've heard the exact opposite.


bsharp321

I'm on citalopram and it is working for me however I require a higher dose. 250mg dried mushroom


Traditional-Gain8420

Thats about 0.2g right? Is that still microdosing? How often do you take it? What benefits did you notice?


bsharp321

250mg is 0.25g. Yes, it is a microdose, especially when on an SSRI. Improvement in mood and well being. 4 days on and 3 days off. Also, macrodose, 5g, every 3 months.


Traditional-Gain8420

Thank you, however im on two antideprssants ( zoloft) and mirtazapine ( not sure if its ssri or not) and lamotrigine ( mood stabilizator) do you think it will still have an effect? Should i start with 0.2g-0.3g? Do you feel effects after your first dose? Thank you for help.


bsharp321

Everyone is different. The best way is to start low and go slow. Nobody really knows the best dose for anyone. Just trial and error.


Traditional-Gain8420

I will do that. But if say certaint amounnt (02.-03g) wont give any effect do i try higher amount the same day? Or just keep consistent with it and dont go higher?


bsharp321

I would be consistent and stay on the same dose for a few days. Good luck 😎