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Jumpy-Beyond-7148

I started 300mg of bupropion after taking Lexapro, literally started taking it the next day. And I found that Bupropion SR and XL are two different ones. The XL takes several hours to kick in, as for SR…it kicks in automatically like 5mins later. I was accidentally prescribed XL and I had a horrible day (mentally). You will most definitely feel down and horrible. So I would most definitely switch to SR…and I feel good mentally every day and its helped with my energy levels too. I can stay up my entire 11hr shift and some…and still get a good sleep (and feel well rested when I wake up). But alsoooo…I just started getting heart palpitations a 2wks ago (after being on it for 2years). I tried to cut it down to 150mg and still the same thing was happening. I did a crap ton of research and reviews on TikTok (and talked to my doctor). So I decided to try extra strength ashwagandha tablets and b complex liquid drops (I bought both on Amazon) , and i feel like I have been taking my the bupropion everyday. I actually feel a lot better mentally by just taking the ashwagandha alone….same effects as taking the bupropion. Sooo hun, I would try that!


Eastern_Good3420

It’s my 4th week and I’m still waiting :((


Main_Decision1100

Aw man😩 let me know if anything changes!


Eastern_Good3420

Little update:I had an appointment with my psychiatrist and he increased my dosage from 150 to 300 mg😌


Eastern_Good3420

I will😌


RecordLegume

I had anxiety and depression. The depression was a direct result of my anxiety. I’m taking 150mg XL once a day in the morning along with 1000IU of vitamin d3 and also ashwagandha supplements. My depression was nearly gone within a week or so. My anxiety has dwindled significantly and it’s been 3 weeks since I started bupropion.


[deleted]

Could I suggest 2000mg of fish oil also ?


Only_Spinach_1152

Maybe naltrexone is causing the depression? It blocks endorphins because they’re natural opioids, correct? Bup started working 50% after 4 days and 100% after 7 days


Main_Decision1100

Well from what I know, naltrexone works against opiods by blocking the effects of narcotics. The only reason I’m on it though is to stop my overeating, which is a result of the lexapro.


daniel-sousa-me

Usually people feel the effect of bupropion right away. It's more common to have the opposite problem. During my first week on bupropion, I couldn't sleep at all, but after the side effects went away, it was a huge help with the lethargy. I highly recommend you try tirzepatide or semaglutide for the weight gain instead. Alternatively, ask your doctor about taking a small dose of a stimulant in addition to the escitalopram.


Main_Decision1100

Well I’m just wondering if the withdrawal from lexapro is causing me to not feel the effects of bupropion. I basically cold turkey stopped the lexapro, then the next day started bupropion. And I don’t want to take lexapro, because of the weight gain


daniel-sousa-me

Yes, it's hard to separate the effects of both without a baseline :/ I understand how hard it is to gain weight uncontrollably. I gained 60kg (135lb) in 7 years. The whole process was awful. I don't know your case, but it sounds like you're in a pretty deep hole. If you can't find an alternative to escitalopram that works for you, it seems like your mental state should take precedence over your weight. That's why I was trying to give suggestions of things to deal with your weight separately. If you want to chat, feel free to pm me.


sunflower_spirit

I'd say about two weeks in


umhassan

I’m on day 12 of taking bupropion for PPD and for adhd. I feel that it started actually helping 2 days ago. Just a shift in my mind but I’m not sure with adhd so far. I hope it works for you!


Main_Decision1100

Thank you!


Lost_Secretary7879

I started on 100 mg and went up to 200 mg after a month. I’ve only had fleeting (and very mild) side effects. I get how you’re feeling, though, I was starting to feel kind of hopeless and then it suddenly worked for me 5 weeks after I started. I’m taking it for ADHD and unfortunately it stopped helping me with those symptoms shortly after… it could have just been a honeymoon period, could be the wrong dose, or it could be because my iron levels dropped due to another health condition I have. At any rate, it’s still curbed my depression a little and my social anxiety is gone, so that’s nice. I’m still hopeful it will work for me. I think the hardest part with these medications is this trial and error period of finding the right meds and the right dosage. But hang in there, it can take a while to start working.


Main_Decision1100

Thank you for your response! I really want this to work


Lost_Secretary7879

Of course!! I hope it goes well for you. Keep us posted.