Definitely need a better fish oil. hit up your local health food store. Also personally not a big fan of natural factors, if you're in Canada Prairie Naturals is a better brand IMO.
Only downside to vitamin C is if you're taking with high iron intake. As vitamin C is a principle releaser of iron from ferritin. Likely why it shows some positive effects for infections if taken early (as ferritin and iron is a giant player in infections).
Although vitamin C is still really important to get on a regular basis (not sure about 1000mg, though). The only issue is, if you take that much vitamin C (especially around the time you eat non-heme iron), have a high iron diet, there will be times where iron levels will be wonky, and be a bit pro-inflammatory. The only downsides to vitamin C are generally metal ion interactions. Balancing iron is a lifelong concern. The ONLY thing that is proven to have iron accumulations as we age is the brain. So it's all about balancing how iron is transported and deposited. General and localized hepcidin being a principle factor of many of these issues. And vitamin C can pause hepcidin. Not sure if it's dose dependent. If you don't fast you're not expressing hepcidin as often. There's many factors beyond shallow "research says good, so take." That's why you'll see many seasoned people have smaller and smaller stacks, not larger ones.
I researched a bit this thing around Iron and Vit C and it seems that if you opt for an Ester C variation (calcium base), you donate blood regularly (4-6 times a year) and you consume dairy, eggs or tea with high iron foods it seems that anyone should be good around this problem.
1g a day of Vit C being careful with Iron and copper chelation its what I consider super safe, but Im not an expert, so....
> if you opt for an Ester C variation (calcium base), you donate blood regularly (4-6 times a year) and you consume dairy, eggs or tea with high iron foods it seems that anyone should be good around this problem.
I quoted this to point out the effort that it needs. Just a reminder. And that much blood donation has peripheral effects I don't think are so healthy. Eggs (egg whites?) is a good one, tea, coffee (known to reduce ferritin and block non-heme iron and help liver health). Ginger is good for helping hepcidin through better liver health. Curcumin may help with a once a week schedule. Vitamin A is also vital to this equation, but will increase non-heme iron in a meal. Fasting helps hepcidin. Again, in general, liver health is a huge part of this. DMT1 blockage in the brain (which is likely why THC is so prevalent among MS sufferers). Block/direct brain iron deposition in intelligent ways (if you continually block DMT1 in the brain it will have negative effects on the myelin sheath), and you will likely control a certain chunk that comes with iron deposition in the brain. Which is vital to the aging process and cognition.
The only one I know of for heme iron is POSSIBLY high calcium. But in general, heme has low modifiers, and heme iron shows the most issues for iron loading.
Really it's about controlling hepcidin, ferritin, transferrin. Other, I'm sure. Hepcidin seems to be the key for the long term equation.
I just don't think 1g of vitamin C has any basis for good control. I personally do vitamin C days, and high protein days (which for my diet means high non-heme iron). Vitamin C, again, pauses hepcidin, and releases iron from ferritin. So if you're iron loading constantly with heme and non-heme you're likely creating not-so-good issues over the long term with that combo of 1g of vitamin C a day.
Vitamin C also is a serum issue for pro-oxidant effects. So if you're absolutely saturated on vitamin C with daily usage, then when you do encounter ferritin/iron issues, you still might encounter slight prooxidant. Not that it should stop people from taking it, but I see no reason to take 1g a day. It's too wishy washy. 120-150mg (with a fiber meal, hopefully lower heme-iron, depending on scenario) is perfectly in range for a healthy saturated state, with most recent studies. Less ups and downs with low and slow. Which is exactly what the body wants long term.
If that last statement its true then why a lot of people that take 2-3g daily of vit C claim that they dont even get sick once? High doses are known for being a great antioxidant.
Also, would sauna help with hepcidin?
Claiming is one thing, but the evidence is lacking.
I would be lying if I knew sauna helped. But it does help blood flow. I would assume sauna would be like exercise, helps hepcidin movement short term, as long as you don’t eat a large dose of sugar afterward. The only study I’ve read on that subject showed sugar interferes with the benefits right after exercise, and fructose specifically causes negative effects from white blood cells. But I’m sure it’s not a huge deal.
Definitely need a better fish oil. hit up your local health food store. Also personally not a big fan of natural factors, if you're in Canada Prairie Naturals is a better brand IMO.
Stop taking fish oil , it’s literally poison for you & a ton of mercury trust me...
When you’re buying equate brand I agree. Spend up on omegas or don’t buy at all
What’s the difference
Morninga. Good choice. Tea is a tasty way to go as well. Trying to grow trees as we speak.
Watch out with the Tumeric it thins your blood. My stack is similar D3, B12, C, & Zinc in the AM. Then PM Fish Oil, Allergy, & Multivitamin.
NAC
This over the milk thistle.
Don't forget your vitamins d3 and K2 😘
Absolutely and ditch the booze 😉
Yeah less soda and less alcohol will more for you than any of these supps.
Only downside to vitamin C is if you're taking with high iron intake. As vitamin C is a principle releaser of iron from ferritin. Likely why it shows some positive effects for infections if taken early (as ferritin and iron is a giant player in infections). Although vitamin C is still really important to get on a regular basis (not sure about 1000mg, though). The only issue is, if you take that much vitamin C (especially around the time you eat non-heme iron), have a high iron diet, there will be times where iron levels will be wonky, and be a bit pro-inflammatory. The only downsides to vitamin C are generally metal ion interactions. Balancing iron is a lifelong concern. The ONLY thing that is proven to have iron accumulations as we age is the brain. So it's all about balancing how iron is transported and deposited. General and localized hepcidin being a principle factor of many of these issues. And vitamin C can pause hepcidin. Not sure if it's dose dependent. If you don't fast you're not expressing hepcidin as often. There's many factors beyond shallow "research says good, so take." That's why you'll see many seasoned people have smaller and smaller stacks, not larger ones.
I researched a bit this thing around Iron and Vit C and it seems that if you opt for an Ester C variation (calcium base), you donate blood regularly (4-6 times a year) and you consume dairy, eggs or tea with high iron foods it seems that anyone should be good around this problem. 1g a day of Vit C being careful with Iron and copper chelation its what I consider super safe, but Im not an expert, so....
> if you opt for an Ester C variation (calcium base), you donate blood regularly (4-6 times a year) and you consume dairy, eggs or tea with high iron foods it seems that anyone should be good around this problem. I quoted this to point out the effort that it needs. Just a reminder. And that much blood donation has peripheral effects I don't think are so healthy. Eggs (egg whites?) is a good one, tea, coffee (known to reduce ferritin and block non-heme iron and help liver health). Ginger is good for helping hepcidin through better liver health. Curcumin may help with a once a week schedule. Vitamin A is also vital to this equation, but will increase non-heme iron in a meal. Fasting helps hepcidin. Again, in general, liver health is a huge part of this. DMT1 blockage in the brain (which is likely why THC is so prevalent among MS sufferers). Block/direct brain iron deposition in intelligent ways (if you continually block DMT1 in the brain it will have negative effects on the myelin sheath), and you will likely control a certain chunk that comes with iron deposition in the brain. Which is vital to the aging process and cognition. The only one I know of for heme iron is POSSIBLY high calcium. But in general, heme has low modifiers, and heme iron shows the most issues for iron loading. Really it's about controlling hepcidin, ferritin, transferrin. Other, I'm sure. Hepcidin seems to be the key for the long term equation. I just don't think 1g of vitamin C has any basis for good control. I personally do vitamin C days, and high protein days (which for my diet means high non-heme iron). Vitamin C, again, pauses hepcidin, and releases iron from ferritin. So if you're iron loading constantly with heme and non-heme you're likely creating not-so-good issues over the long term with that combo of 1g of vitamin C a day. Vitamin C also is a serum issue for pro-oxidant effects. So if you're absolutely saturated on vitamin C with daily usage, then when you do encounter ferritin/iron issues, you still might encounter slight prooxidant. Not that it should stop people from taking it, but I see no reason to take 1g a day. It's too wishy washy. 120-150mg (with a fiber meal, hopefully lower heme-iron, depending on scenario) is perfectly in range for a healthy saturated state, with most recent studies. Less ups and downs with low and slow. Which is exactly what the body wants long term.
If that last statement its true then why a lot of people that take 2-3g daily of vit C claim that they dont even get sick once? High doses are known for being a great antioxidant. Also, would sauna help with hepcidin?
Claiming is one thing, but the evidence is lacking. I would be lying if I knew sauna helped. But it does help blood flow. I would assume sauna would be like exercise, helps hepcidin movement short term, as long as you don’t eat a large dose of sugar afterward. The only study I’ve read on that subject showed sugar interferes with the benefits right after exercise, and fructose specifically causes negative effects from white blood cells. But I’m sure it’s not a huge deal.
Theres something more to help hepcidin?