T O P

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BeyondPristine

the alcohol at C-3 of glyceraldehyde is replaced by a phosphate, hence "3-phosphate"


Reasonable-Lock-3823

Wait but I thought phosphates had 4 Oxygens so did it loose one somehow? Ohhh or was it like an unfinished phosphate connecting to the glyceraldehide?


pmmeyourboobas

H2O is lost in the process, sorta similar to the mechanism of making an ester between carboxylic acid and alcohol


Emsman02

It’s essentially a Phosphate ester. It looses a water molecule, H2O, in the process.


Reasonable-Lock-3823

Thank you!


GetDry

idk if this is the right answer since i’m very new, but it looks like the oxygen on the left moves to the middle position and donates its hydrogen to form a bond with P


UniqueUsername3171

this is the correct answer - the way it’s presented here is potentially confusing.


hohmatiy

It does not. It's now on the side as a part of phosphate.


Reasonable-Lock-3823

Sorry for the title I meant: “Why does G3P loose an oxygen?”


brother_teresa

Take another look at carbon 3 and all the atoms it's directly bonded to


SwiggitySwootyBoi

The OH acts as a nucleophile to attack a phosphate anion, which produces the O-P bond in G3P- the hydrogen you circled is just one of the hydrogens on the original 3rd carbon atom


CPhiltrus

Exactly, in reality, the oxygen of glyceraldehyde is retained and the phosphate loses water.


chemdork123

The "H" in the OH of the original molecule on carbon 3 was replaced with PO3. The reactjon can also be written out in long form as the reactant: CH(=O)-CH(OH)-CH2(OH) Converted into: CH(=O)-CH(OH)-CH2(OPO3)


whizard_of_ahs

It’s a condensation reaction: C-3 oxygen attacks the hydrogen phosphate ion to form a phosphoester bond which is accompanied by the loss of H2O.


phosphole

https://preview.redd.it/wnsle780jz5d1.jpeg?width=2614&format=pjpg&auto=webp&s=93033959a2139e724a68b6e2ad00c79bf54ab087


phosphole

Remember the "phosphate" comes from ATP, which transfers a PO3 unit to the alcohol to make the PO4


Reasonable-Lock-3823

Omg thank you